Investigation of the Effect on the Albumin Binding Moiety for the Pharmacokinetic Properties of <sup>68</sup>Ga-, <sup>205/206</sup>Bi-, and <sup>177</sup>Lu-Labeled NAPamide-Based Radiopharmaceuticals
Although radiolabeled alpha-melanocyte stimulating hormone-analogue NAPamide derivatives are valuable melanoma-specific diagnostic probes, their rapid elimination kinetics and high renal uptake may preclude them from being used in clinical settings. We aimed at improving the pharmacokinetics of radi...
Main Authors: | Dániel Szücs, Judit P. Szabó, Viktória Arató, Barbara Gyuricza, Dezső Szikra, Imre Tóth, Zita Képes, György Trencsényi, Anikó Fekete |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-09-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/16/9/1280 |
Similar Items
-
Therapeutic Performance Evaluation of <sup>213</sup>Bi-Labelled Aminopeptidase N (APN/CD13)-Affine NGR-Motif ([<sup>213</sup>Bi]Bi-DOTAGA-cKNGRE) in Experimental Tumour Model: A Treasured Tailor for Oncology
by: Zita Képes, et al.
Published: (2023-02-01) -
The Synthesis and Preclinical Investigation of Lactosamine-Based Radiopharmaceuticals for the Detection of Galectin-3-Expressing Melanoma Cells
by: Barbara Gyuricza, et al.
Published: (2022-11-01) -
Preliminary Evaluation of Iron Oxide Nanoparticles Radiolabeled with <sup>68</sup>Ga and <sup>177</sup>Lu as Potential Theranostic Agents
by: Evangelia-Alexandra Salvanou, et al.
Published: (2022-07-01) -
Preparation, Radiolabeling with <sup>68</sup>Ga/<sup>177</sup>Lu and Preclinical Evaluation of Novel Angiotensin Peptide Analog: A New Class of Peptides for Breast Cancer Targeting
by: Subhani M. Okarvi
Published: (2023-11-01) -
[<sup>18</sup>F]fluoride Activation and <sup>18</sup>F-Labelling in Hydrous Conditions—Towards a Microfluidic Synthesis of PET Radiopharmaceuticals
by: Olga Ovdiichuk, et al.
Published: (2023-12-01)