A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route

A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route

The use of nanocarrier delivery systems for direct nose to brain drug delivery shows promise for achieving increased brain drug levels as compared to simple solution systems. An example of such nanocarriers is emulsomes formed from lipid cores surrounded and stabilised by a corona of phospholipids (...

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Bibliographic Details
Main Authors: Ghada M. El-Zaafarany, Mahmoud E. Soliman, Samar Mansour, Marco Cespi, Giovanni Filippo Palmieri, Lisbeth Illum, Luca Casettari, Gehanne A. S. Awad
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Pharmaceutics
Subjects:
nose to brain delivery
antiepileptic drug
drug delivery
block copolymers
thermogel system
Online Access:https://www.mdpi.com/1999-4923/10/4/217

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