In vitro evaluation of cutaneous penetration of acyclovir from semisolid commercial formulations and relation with its effective antiviral concentration

In vitro evaluation of cutaneous penetration of acyclovir from semisolid commercial formulations and relation with its effective antiviral concentration

ABSTRACT The evaluation of drug permeation/penetration of semisolid formulations into animal skin can be useful to supplement the pharmaceutical equivalence. This paper describes the in vitro assessment of acyclovir (ACV) into porcine skin from commercial formulations with etermination of drug conce...

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Bibliographic Details
Main Authors: Rafaela Martins Sponchiado, Leticia Malgarim Cordenonsi, Nathalie Ribeiro Wingert, Bibiana Verlindo de Araujo, Nadia Maria Volpato
Format: Article
Language:English
Published: Universidade de São Paulo
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Acyclovir/skin penetration/in vitro studies
Acyclovir/semisolid formulations
Acyclovir/pharmaceutical equivalence.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000300483&lng=en&tlng=en

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