Role of Inflammatory Mechanisms in Major Depressive Disorder: From Etiology to Potential Pharmacological Targets

Role of Inflammatory Mechanisms in Major Depressive Disorder: From Etiology to Potential Pharmacological Targets

The involvement of central and peripheral inflammation in the pathogenesis and prognosis of major depressive disorder (MDD) has been demonstrated. The increase of pro-inflammatory cytokines (interleukin (IL)-1β, IL-6, IL-18, and TNF-α) in individuals with depression may elicit neuroinflammatory proc...

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Bibliographic Details
Main Authors: Bruna R. Kouba, Laura de Araujo Borba, Pedro Borges de Souza, Joana Gil-Mohapel, Ana Lúcia S. Rodrigues
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
anti-inflammatory approaches
gut dysbiosis
inflammation
major depressive disorder
Online Access:https://www.mdpi.com/2073-4409/13/5/423

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