Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases
Zanthoxylum bungeanum Maxim., commonly known as Chinese prickly ash, is a well-known spice and traditional Chinese medicine ingredient with a rich history of use in treating inflammatory conditions. This review provides a comprehensive overview of the botanical classification, traditional applicatio...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1305886/full |
| _version_ | 1827374157849952256 |
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| author | Jinxin Qi Jinxin Qi Zhaoping Pan Zhaoping Pan Xiaoyun Wang Xiaoyun Wang Nan Zhang Gu He Gu He Xian Jiang Xian Jiang |
| author_facet | Jinxin Qi Jinxin Qi Zhaoping Pan Zhaoping Pan Xiaoyun Wang Xiaoyun Wang Nan Zhang Gu He Gu He Xian Jiang Xian Jiang |
| author_sort | Jinxin Qi |
| collection | DOAJ |
| description | Zanthoxylum bungeanum Maxim., commonly known as Chinese prickly ash, is a well-known spice and traditional Chinese medicine ingredient with a rich history of use in treating inflammatory conditions. This review provides a comprehensive overview of the botanical classification, traditional applications, and anti-inflammatory effects of Z. bungeanum, with a specific focus on its polyphenolic components. These polyphenols have exhibited considerable promise, as evidenced by preclinical studies in animal models, suggesting their therapeutic potential in human inflammatory diseases such as ulcerative colitis, arthritis, asthma, chronic obstructive pulmonary disease, cardiovascular disease, and neurodegenerative conditions. This positions them as a promising class of natural compounds with the potential to enhance human well-being. However, further research is necessary to fully elucidate their mechanisms of action and develop safe and effective therapeutic applications. |
| first_indexed | 2024-03-08T11:28:46Z |
| format | Article |
| id | doaj.art-23a86d6d930b4111b5ae6836893ea974 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-03-08T11:28:46Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-23a86d6d930b4111b5ae6836893ea9742024-01-26T04:32:02ZengFrontiers Media S.A.Frontiers in Immunology1664-32242024-01-011510.3389/fimmu.2024.13058861305886Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseasesJinxin Qi0Jinxin Qi1Zhaoping Pan2Zhaoping Pan3Xiaoyun Wang4Xiaoyun Wang5Nan Zhang6Gu He7Gu He8Xian Jiang9Xian Jiang10Department of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaLaboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaLaboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaLaboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaLaboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaLaboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, ChinaZanthoxylum bungeanum Maxim., commonly known as Chinese prickly ash, is a well-known spice and traditional Chinese medicine ingredient with a rich history of use in treating inflammatory conditions. This review provides a comprehensive overview of the botanical classification, traditional applications, and anti-inflammatory effects of Z. bungeanum, with a specific focus on its polyphenolic components. These polyphenols have exhibited considerable promise, as evidenced by preclinical studies in animal models, suggesting their therapeutic potential in human inflammatory diseases such as ulcerative colitis, arthritis, asthma, chronic obstructive pulmonary disease, cardiovascular disease, and neurodegenerative conditions. This positions them as a promising class of natural compounds with the potential to enhance human well-being. However, further research is necessary to fully elucidate their mechanisms of action and develop safe and effective therapeutic applications.https://www.frontiersin.org/articles/10.3389/fimmu.2024.1305886/fullZanthoxylum bungeanum Maxim.inflammationpolyphenolsinflammatory diseaseNF-κB |
| spellingShingle | Jinxin Qi Jinxin Qi Zhaoping Pan Zhaoping Pan Xiaoyun Wang Xiaoyun Wang Nan Zhang Gu He Gu He Xian Jiang Xian Jiang Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases Frontiers in Immunology Zanthoxylum bungeanum Maxim. inflammation polyphenols inflammatory disease NF-κB |
| title | Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases |
| title_full | Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases |
| title_fullStr | Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases |
| title_full_unstemmed | Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases |
| title_short | Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases |
| title_sort | research advances of zanthoxylum bungeanum maxim polyphenols in inflammatory diseases |
| topic | Zanthoxylum bungeanum Maxim. inflammation polyphenols inflammatory disease NF-κB |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1305886/full |
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