Molecular Mechanism Underlying Hypoxic Preconditioning-Promoted Mitochondrial Translocation of DJ-1 in Hypoxia/Reoxygenation H9c2 Cells

Molecular Mechanism Underlying Hypoxic Preconditioning-Promoted Mitochondrial Translocation of DJ-1 in Hypoxia/Reoxygenation H9c2 Cells

DJ-1 was recently reported to be involved in the cardioprotection of hypoxic preconditioning (HPC) against hypoxia/reoxygenation (H/R)-induced oxidative stress damage, by preserving mitochondrial complex I activity and, subsequently, inhibiting mitochondrial reactive oxygen species (ROS) generation....

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Bibliographic Details
Main Authors: Yi-Zhang Deng, Lin Xiao, Le Zhao, Le-Jia Qiu, Zhao-Xia Ma, Xing-Wang Xu, Hao-Yue Liu, Ting-Ting Zhou, Xue-Ying Wang, Lei Tang, He-Ping Chen
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Molecules
Subjects:
dj-1
mitochondria translocation
hypoxic preconditioning
grp75
oxidative stress
hypoxia/reoxygenation
Online Access:https://www.mdpi.com/1420-3049/25/1/71

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