The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c Mice
Many studies suggest that noise stress could damage many body systems such as nervous and endocrine systems, so the goal of this study was to demonstrate how the levels of neurotransmitters and sex hormones in mature male and female mice are affected by different noise stress exposure durations? In...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Arabic |
| Published: |
Al-Mustansiriyah University
2023-02-01
|
| Series: | Mustansiriyah Journal of Science |
| Subjects: | |
| Online Access: | https://mjs.uomustansiriyah.edu.iq/index.php/MJS/article/view/1321 |
| _version_ | 1797894107505360896 |
|---|---|
| author | Zainab A. A. Al-Shammary Sabah A. Hameid Jamela Jouda |
| author_facet | Zainab A. A. Al-Shammary Sabah A. Hameid Jamela Jouda |
| author_sort | Zainab A. A. Al-Shammary |
| collection | DOAJ |
| description |
Many studies suggest that noise stress could damage many body systems such as nervous and endocrine systems, so the goal of this study was to demonstrate how the levels of neurotransmitters and sex hormones in mature male and female mice are affected by different noise stress exposure durations? In this study, 60 Balb/C mice (males and females) were used. Fifty mice were exposed to 90dB noise stress for 4h/daily and were scarified in different time points; 1,7,14,21, and 28 days while the rest 10mice were not exposed to noise stress and they serve as control. After the end of the experiment, the blood was collected and the serum samples were used to determine neurotransmitters levels, serotonin (5-HT) and noradrenaline (NA), and hormones levels included testosterone, estrogen and cortisol levels. The findings showed that neurotransmitters levels were significantly higher in mice exposed to noise stress for 1,8,14, and 21days which was non-significant decrease compared to the control in the 28-day stress group. While the levels of cortisone were continuously rising in the exposed noise stress mice groups with the length of duration, the levels of estrogen in female and testosterone in male were continuously decreasing. Interestingly, the levels of neurotransmitters and cortisol were significantly higher in females than males in all noise stress groups. Additionally, these effects completely differ after 28 days of noise exposure, which needs more future studies to prove the risk of exposure to this type of stress on the body systems.
|
| first_indexed | 2024-04-10T07:03:34Z |
| format | Article |
| id | doaj.art-23ac3f9c85e941a3b72369234dbf6375 |
| institution | Directory Open Access Journal |
| issn | 1814-635X 2521-3520 |
| language | Arabic |
| last_indexed | 2024-04-10T07:03:34Z |
| publishDate | 2023-02-01 |
| publisher | Al-Mustansiriyah University |
| record_format | Article |
| series | Mustansiriyah Journal of Science |
| spelling | doaj.art-23ac3f9c85e941a3b72369234dbf63752023-02-27T10:50:39ZaraAl-Mustansiriyah UniversityMustansiriyah Journal of Science1814-635X2521-35202023-02-0133510.23851/mjs.v33i5.1321The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c MiceZainab A. A. Al-Shammary0Sabah A. Hameid1Jamela Jouda2AL-Esraa University College, Baghdad, IRAQ.Al Nukhba University College, Baghdad, IRAQ.Biology Department, College of Science, Mustansiriyah University, 10052 Baghdad, IRAQ. Many studies suggest that noise stress could damage many body systems such as nervous and endocrine systems, so the goal of this study was to demonstrate how the levels of neurotransmitters and sex hormones in mature male and female mice are affected by different noise stress exposure durations? In this study, 60 Balb/C mice (males and females) were used. Fifty mice were exposed to 90dB noise stress for 4h/daily and were scarified in different time points; 1,7,14,21, and 28 days while the rest 10mice were not exposed to noise stress and they serve as control. After the end of the experiment, the blood was collected and the serum samples were used to determine neurotransmitters levels, serotonin (5-HT) and noradrenaline (NA), and hormones levels included testosterone, estrogen and cortisol levels. The findings showed that neurotransmitters levels were significantly higher in mice exposed to noise stress for 1,8,14, and 21days which was non-significant decrease compared to the control in the 28-day stress group. While the levels of cortisone were continuously rising in the exposed noise stress mice groups with the length of duration, the levels of estrogen in female and testosterone in male were continuously decreasing. Interestingly, the levels of neurotransmitters and cortisol were significantly higher in females than males in all noise stress groups. Additionally, these effects completely differ after 28 days of noise exposure, which needs more future studies to prove the risk of exposure to this type of stress on the body systems. https://mjs.uomustansiriyah.edu.iq/index.php/MJS/article/view/1321Noise stressnoradrenalineserotonintestosteroneestrogen |
| spellingShingle | Zainab A. A. Al-Shammary Sabah A. Hameid Jamela Jouda The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c Mice Mustansiriyah Journal of Science Noise stress noradrenaline serotonin testosterone estrogen |
| title | The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c Mice |
| title_full | The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c Mice |
| title_fullStr | The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c Mice |
| title_full_unstemmed | The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c Mice |
| title_short | The Relation Between the Noise Stress Effects and Neurotransmitters, Sex Hormones Levels in the Male and Female Balb/c Mice |
| title_sort | relation between the noise stress effects and neurotransmitters sex hormones levels in the male and female balb c mice |
| topic | Noise stress noradrenaline serotonin testosterone estrogen |
| url | https://mjs.uomustansiriyah.edu.iq/index.php/MJS/article/view/1321 |
| work_keys_str_mv | AT zainabaaalshammary therelationbetweenthenoisestresseffectsandneurotransmitterssexhormoneslevelsinthemaleandfemalebalbcmice AT sabahahameid therelationbetweenthenoisestresseffectsandneurotransmitterssexhormoneslevelsinthemaleandfemalebalbcmice AT jamelajouda therelationbetweenthenoisestresseffectsandneurotransmitterssexhormoneslevelsinthemaleandfemalebalbcmice AT zainabaaalshammary relationbetweenthenoisestresseffectsandneurotransmitterssexhormoneslevelsinthemaleandfemalebalbcmice AT sabahahameid relationbetweenthenoisestresseffectsandneurotransmitterssexhormoneslevelsinthemaleandfemalebalbcmice AT jamelajouda relationbetweenthenoisestresseffectsandneurotransmitterssexhormoneslevelsinthemaleandfemalebalbcmice |