Case Report: Chemotherapy-Associated Systemic Sclerosis: Is DNA Damage to Blame?

Case Report: Chemotherapy-Associated Systemic Sclerosis: Is DNA Damage to Blame?

Systemic sclerosis, also known as scleroderma, is an autoimmune disease characterized by cutaneous and visceral fibrosis, immune dysregulation, and vasculopathy. Generally, the degree of skin fibrosis is associated with an increased likelihood of visceral organ involvement. Its pathogenesis is poorl...

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Bibliographic Details
Main Authors: Amy X. Du, Robert Gniadecki, Jan Storek, Mohamed Osman
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medicine
Subjects:
scleroderma
systemic sclerosis
chemotherapy
DNA damage
hematopoietic cell transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.855740/full

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