The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis
Abstract Globally, more than 33 million people are living with rheumatic heart disease (RHD). A high prevalence of the disease is observed in people with poor socio-economic status, overcrowding, and low access to medical facilities. Even though different studies have been conducted in different set...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-10-01
|
| Series: | Tropical Diseases, Travel Medicine and Vaccines |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40794-023-00192-y |
| _version_ | 1797578001804689408 |
|---|---|
| author | Hiwot Berhanu Yimer Mekonnen Abdulhalik Workicho Kalkidan Hassen Zenebe Negeri Morankar Sudhakar Shimelis Mitiku Andualem Mossie |
| author_facet | Hiwot Berhanu Yimer Mekonnen Abdulhalik Workicho Kalkidan Hassen Zenebe Negeri Morankar Sudhakar Shimelis Mitiku Andualem Mossie |
| author_sort | Hiwot Berhanu |
| collection | DOAJ |
| description | Abstract Globally, more than 33 million people are living with rheumatic heart disease (RHD). A high prevalence of the disease is observed in people with poor socio-economic status, overcrowding, and low access to medical facilities. Even though different studies have been conducted in different settings, there is no reliable data regarding RHD prevalence. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled prevalence of RHD in Ethiopia. PubMed/Medline, SCOPUS, HINARI, and Google Scholar databases were used to search for peer-reviewed articles. Articles published in English between the years 1992 and 2022 September were considered. The pooled prevalence of RHD was calculated using a random-effect model at a 95% confidence interval, including the weight of each study. Finally, statistical meta-analysis STATA version 16.0 software was used to calculate the pooled prevalence of RHD.A total of twelve cross-sectional studies were included in the meta-analysis. Individual study prevalence ranges from 0.32 to 32.78%. The pooled prevalence of RHD was 3.19% (95% CI: 1.46–5.56%). The prevalence was higher among the population who visited hospitals at 5.42% (95% CI: 1.09–12.7%) compared to schoolchildren at 0.73% (95% CI: 0.30–1.34%) and community-based studies at 3.83% (95% CI: 3.16–4.55%). Addis Ababa had the lowest prevalence of RHD (0.75% (95% CI: 0.38–1.25%), whereas the highest prevalence was observed in the Amhara region (8.95% (95% CI: 7.21–11.06%). A significant variation in the overall estimated prevalence of RHD was not observed between males and females. Trial registration Protocol registration (PROSPERO): CRD42021251553, Date of registration May 28 2021 |
| first_indexed | 2024-03-10T22:16:59Z |
| format | Article |
| id | doaj.art-23b1e682726c4363800bfe4bef21ab6b |
| institution | Directory Open Access Journal |
| issn | 2055-0936 |
| language | English |
| last_indexed | 2024-03-10T22:16:59Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Tropical Diseases, Travel Medicine and Vaccines |
| spelling | doaj.art-23b1e682726c4363800bfe4bef21ab6b2023-11-19T12:24:31ZengBMCTropical Diseases, Travel Medicine and Vaccines2055-09362023-10-019111110.1186/s40794-023-00192-yThe prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysisHiwot Berhanu0Yimer Mekonnen1Abdulhalik Workicho2Kalkidan Hassen3Zenebe Negeri4Morankar Sudhakar5Shimelis Mitiku6Andualem Mossie7Department of Biomedical Sciences, Faculty of Medical Science, Jimma Institute of Health, Jimma UniversityDepartment of Pharmacy, Faculty of Health Sciences, Jimma Institute of Health, Jimma UniversityDepartment of Epidemiology, Institute of Health, Jimma UniversityDepartment of Nutrition and Dietetics, Institute of Health, Jimma UniversityDepartment of Biomedical Sciences, Faculty of Medical Science, Jimma Institute of Health, Jimma UniversityDepartment of Health, Behavior and Society, Faculty of Public Health, Ethiopian Evidence Based Health Care CenterInstitute of HealthJimma UniversityDepartment of Biomedical Sciences, Faculty of Medical Science, Jimma Institute of Health, Jimma UniversityDepartment of Biomedical Sciences, Faculty of Medical Science, Jimma Institute of Health, Jimma UniversityAbstract Globally, more than 33 million people are living with rheumatic heart disease (RHD). A high prevalence of the disease is observed in people with poor socio-economic status, overcrowding, and low access to medical facilities. Even though different studies have been conducted in different settings, there is no reliable data regarding RHD prevalence. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled prevalence of RHD in Ethiopia. PubMed/Medline, SCOPUS, HINARI, and Google Scholar databases were used to search for peer-reviewed articles. Articles published in English between the years 1992 and 2022 September were considered. The pooled prevalence of RHD was calculated using a random-effect model at a 95% confidence interval, including the weight of each study. Finally, statistical meta-analysis STATA version 16.0 software was used to calculate the pooled prevalence of RHD.A total of twelve cross-sectional studies were included in the meta-analysis. Individual study prevalence ranges from 0.32 to 32.78%. The pooled prevalence of RHD was 3.19% (95% CI: 1.46–5.56%). The prevalence was higher among the population who visited hospitals at 5.42% (95% CI: 1.09–12.7%) compared to schoolchildren at 0.73% (95% CI: 0.30–1.34%) and community-based studies at 3.83% (95% CI: 3.16–4.55%). Addis Ababa had the lowest prevalence of RHD (0.75% (95% CI: 0.38–1.25%), whereas the highest prevalence was observed in the Amhara region (8.95% (95% CI: 7.21–11.06%). A significant variation in the overall estimated prevalence of RHD was not observed between males and females. Trial registration Protocol registration (PROSPERO): CRD42021251553, Date of registration May 28 2021https://doi.org/10.1186/s40794-023-00192-yRheumatic heart diseasePrevalenceEchocardiographyEthiopia |
| spellingShingle | Hiwot Berhanu Yimer Mekonnen Abdulhalik Workicho Kalkidan Hassen Zenebe Negeri Morankar Sudhakar Shimelis Mitiku Andualem Mossie The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis Tropical Diseases, Travel Medicine and Vaccines Rheumatic heart disease Prevalence Echocardiography Ethiopia |
| title | The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis |
| title_full | The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis |
| title_fullStr | The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis |
| title_full_unstemmed | The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis |
| title_short | The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis |
| title_sort | prevalence of rheumatic heart disease in ethiopia a systematic review and meta analysis |
| topic | Rheumatic heart disease Prevalence Echocardiography Ethiopia |
| url | https://doi.org/10.1186/s40794-023-00192-y |
| work_keys_str_mv | AT hiwotberhanu theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT yimermekonnen theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT abdulhalikworkicho theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT kalkidanhassen theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT zenebenegeri theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT morankarsudhakar theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT shimelismitiku theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT andualemmossie theprevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT hiwotberhanu prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT yimermekonnen prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT abdulhalikworkicho prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT kalkidanhassen prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT zenebenegeri prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT morankarsudhakar prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT shimelismitiku prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis AT andualemmossie prevalenceofrheumaticheartdiseaseinethiopiaasystematicreviewandmetaanalysis |