S-allylcysteine suppresses ovarian cancer cell proliferation by DNA methylation through DNMT1

S-allylcysteine suppresses ovarian cancer cell proliferation by DNA methylation through DNMT1

Abstract Background The anti-tumor effects of S-allylcysteine (SAC), a water-soluble garlic derivative, on human ovarian cancer cells have been previous studied in vitro and in vivo models but the precise epigenetic molecular mechanisms are still unclear. This study aimed to investigate the epigenet...

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Bibliographic Details
Main Authors: Yasi Xu, Dan Su, Lucheng Zhu, Shirong Zhang, Shenglin Ma, Kan Wu, Qiang Yuan, Nengming Lin
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Ovarian Research
Subjects:
Epigenetic
DNA methylation
S-allylcysteine
Ovarian cancer
Online Access:http://link.springer.com/article/10.1186/s13048-018-0412-1

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