Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in <italic toggle="yes">Salmonella</italic>

Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in <italic toggle="yes">Salmonella</italic>

ABSTRACT Highly expressed genes are commonly located close to the origin of replication of bacterial chromosomes (OriC). This location skew is thought to reflect selective advantages associated with gene dosage effects during the replication cycle. The expression of constitutively expressed genes ca...

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Bibliographic Details
Main Authors: Eva Garmendia, Gerrit Brandis, Diarmaid Hughes
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
chromosome organization
EF-Tu
location bias
tufB
Online Access:https://journals.asm.org/doi/10.1128/mBio.01446-18

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