Endothelin B receptors contribute to retinal ganglion cell loss in a rat model of glaucoma.

Endothelin B receptors contribute to retinal ganglion cell loss in a rat model of glaucoma.

Glaucoma is an optic neuropathy, commonly associated with elevated intraocular pressure (IOP) characterized by optic nerve degeneration, cupping of the optic disc, and loss of retinal ganglion cells which could lead to loss of vision. Endothelin-1 (ET-1) is a 21-amino acid vasoactive peptide that pl...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Alena Z Minton, Nitasha R Phatak, Dorota L Stankowska, Shaoqing He, Hai-Ying Ma, Brett H Mueller, Ming Jiang, Robert Luedtke, Shaohua Yang, Colby Brownlee, Raghu R Krishnamoorthy
Format:	Artikel
Sprache:	English
Veröffentlicht:	Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:	PLoS ONE
Online Zugang:	http://europepmc.org/articles/PMC3423444?pdf=render

Ähnliche Einträge

Involvement of AP-1 and C/EBPβ in upregulation of endothelin B (ETB) receptor expression in a rodent model of glaucoma.
von: Shaoqing He, et al.
Veröffentlicht: (2013-01-01)

The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats
von: Bindu Kodati, et al.
Veröffentlicht: (2023-06-01)

Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death
von: Olivia J. Marola, et al.
Veröffentlicht: (2022-04-01)

Mechanisms contributing to inhibition of retinal ganglion cell death by cell permeable peptain-1 under glaucomatous stress
von: Gretchen A. Johnson, et al.
Veröffentlicht: (2024-06-01)

Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma
von: Mi-Hyun Nam, et al.
Veröffentlicht: (2022-11-01)

Mitochondria-associated endoplasmic reticulum membranes (MAMs) and their role in glaucomatous retinal ganglion cell degeneration—a mini review
von: Jennifer H. Pham, et al.
Veröffentlicht: (2023-05-01)

Intrinsically photosensitive retinal ganglion cells in glaucoma
von: Jingyi Gao, et al.
Veröffentlicht: (2022-09-01)

The Role of Retinal Ganglion Cell Structure and Function in Glaucoma
von: Kathy Ming Feng, et al.
Veröffentlicht: (2023-12-01)

Retinal ganglion cells adapt to ionic stress in experimental glaucoma
von: Andrew M. Boal, et al.
Veröffentlicht: (2023-03-01)

Involvement of endothelins in neuroprotection of valosin-containing protein modulators against retinal ganglion cell damage
von: Mami Kusaka, et al.
Veröffentlicht: (2022-09-01)

Modulating mitochondrial calcium channels (TRPM2/MCU/NCX) as a therapeutic strategy for neurodegenerative disorders
von: Gretchen A. Johnson, et al.
Veröffentlicht: (2023-10-01)

HIF-1 expression in retinal ganglion cells and optic nerve axons in glaucoma HIF-1 expression in retinal ganglion cells and optic nerve axons in glaucoma
von: Joanna Reszeć, et al.
Veröffentlicht: (2012-10-01)

A Neuroprotective Peptide Modulates Retinal cAMP Response Element-Binding Protein (CREB), Synapsin I (SYN1), and Growth-Associated Protein 43 (GAP43) in Rats with Silicone Oil-Induced Ocular Hypertension
von: Gretchen A. Johnson, et al.
Veröffentlicht: (2025-02-01)

Antioxidant effect of gallic acid on retinal ganglion cells in glaucoma model
von: Ruping Jiang, et al.
Veröffentlicht: (2024-06-01)

Ripa-56 protects retinal ganglion cells in glutamate-induced retinal excitotoxic model of glaucoma
von: Lemeng Feng, et al.
Veröffentlicht: (2024-02-01)

Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function in In Vivo Model of Glaucoma in Rat and Retinal Ganglion Cell Culture In Vitro
von: Feng-Juan Gao, et al.
Veröffentlicht: (2017-09-01)

Neuroprotection of Rodent and Human Retinal Ganglion Cells In Vitro/Ex Vivo by the Hybrid Small Molecule SA-2
von: Jennifer H. Pham, et al.
Veröffentlicht: (2022-11-01)

Role of mitophagy in ocular neurodegeneration
von: Calvin D. Brooks, et al.
Veröffentlicht: (2023-10-01)

PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis
von: Jingyi Luo, et al.
Veröffentlicht: (2023-07-01)

Loss of Sarm1 reduces retinal ganglion cell loss in chronic glaucoma
von: Huilan Zeng, et al.
Veröffentlicht: (2024-02-01)

Ferroptosis and glaucoma: implications in retinal ganglion cell damage and optic nerve survival
von: Ming Yang, et al.
Veröffentlicht: (2023-01-01)

Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma
von: Maciej Daniszewski, et al.
Veröffentlicht: (2022-06-01)

Evaluation of Macular and Retinal Ganglion Cell Count Estimates for Detecting and Staging Glaucoma
von: Yali Wu, et al.
Veröffentlicht: (2021-10-01)

NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells
von: Sarah Naguib, et al.
Veröffentlicht: (2023-10-01)

Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma.
von: Harry A Quigley, et al.
Veröffentlicht: (2015-01-01)

Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma
von: Michal Geva, et al.
Veröffentlicht: (2021-11-01)

Plasma endothelin-1 and endothelin-A receptor concentrations in patients with primary open-angle glaucoma
von: Bilyana Mihaylova, et al.
Veröffentlicht: (2017-07-01)

Neuroprotective effects of resveratrol on retinal ganglion cells in glaucoma in rodents: A narrative review
von: Maryam Golmohammadi, et al.
Veröffentlicht: (2024-06-01)

Analysis of Ganglion Cell Complex and Retinal Nerve Fiber Layer Thickness in Glaucoma Diagnosis
von: Sania Vidas, et al.
Veröffentlicht: (2017-01-01)

cGMP Signaling in the Neurovascular Unit—Implications for Retinal Ganglion Cell Survival in Glaucoma
von: Ameer A. Haider, et al.
Veröffentlicht: (2022-11-01)

The relationship between visual field index and estimated number of retinal ganglion cells in glaucoma.
von: Amir H Marvasti, et al.
Veröffentlicht: (2013-01-01)

Ganglion cell analysis versus retinal nerve fiber layer thickness in glaucoma diagnosis
von: Tarek Tawfik Soliman, et al.
Veröffentlicht: (2019-01-01)

Asiatic Acid Prevents Retinal Ganglion Cell Apoptosis in a Rat Model of Glaucoma
von: Wanjing Huang, et al.
Veröffentlicht: (2018-07-01)

Progress in Gene Therapy to Prevent Retinal Ganglion Cell Loss in Glaucoma and Leber’s Hereditary Optic Neuropathy
von: Sara E. Ratican, et al.
Veröffentlicht: (2018-01-01)

Opposing roles for membrane bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death.
von: Meredith S Gregory, et al.
Veröffentlicht: (2011-03-01)

RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy
von: Hongmei Qian, et al.
Veröffentlicht: (2024-01-01)

RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy.
von: Hongmei Qian, et al.
Veröffentlicht: (2024-01-01)

Angiotensin II-Related Activation of Scleral Fibroblasts and Their Role on Retinal Ganglion Cell Death in Glaucoma
von: Si-Eun Oh, et al.
Veröffentlicht: (2023-04-01)

Effect of geranylgeranylacetone on the protection of retinal ganglion cells in a mouse model of normal tension glaucoma
von: Zhenyu Dong, et al.
Veröffentlicht: (2016-10-01)

Risk Factors in Normal-Tension Glaucoma and High-Tension Glaucoma in relation to Polymorphisms of Endothelin-1 Gene and Endothelin-1 Receptor Type A Gene
von: Dominika Wróbel-Dudzińska, et al.
Veröffentlicht: (2015-01-01)