Endothelin B receptors contribute to retinal ganglion cell loss in a rat model of glaucoma.

Glaucoma is an optic neuropathy, commonly associated with elevated intraocular pressure (IOP) characterized by optic nerve degeneration, cupping of the optic disc, and loss of retinal ganglion cells which could lead to loss of vision. Endothelin-1 (ET-1) is a 21-amino acid vasoactive peptide that pl...

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Bibliografische gegevens
Hoofdauteurs: Alena Z Minton, Nitasha R Phatak, Dorota L Stankowska, Shaoqing He, Hai-Ying Ma, Brett H Mueller, Ming Jiang, Robert Luedtke, Shaohua Yang, Colby Brownlee, Raghu R Krishnamoorthy
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2012-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3423444?pdf=render