Endothelin B receptors contribute to retinal ganglion cell loss in a rat model of glaucoma.

Glaucoma is an optic neuropathy, commonly associated with elevated intraocular pressure (IOP) characterized by optic nerve degeneration, cupping of the optic disc, and loss of retinal ganglion cells which could lead to loss of vision. Endothelin-1 (ET-1) is a 21-amino acid vasoactive peptide that pl...

Полное описание

Библиографические подробности
Главные авторы: Alena Z Minton, Nitasha R Phatak, Dorota L Stankowska, Shaoqing He, Hai-Ying Ma, Brett H Mueller, Ming Jiang, Robert Luedtke, Shaohua Yang, Colby Brownlee, Raghu R Krishnamoorthy
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2012-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3423444?pdf=render