Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats

Welding is described as one of the most hazardous occupations. The study aims to determine the influence of metal welding fumes on kidney function parameters in blood of the exposed animals. The fumes were collected from welding sites during the activity by a skilled welder. One hundred thirty exper...

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Main Authors: Ibrahim Lawal Abdullahi, Ali Sani
Format: Article
Language:English
Published: Athens Institute for Education and Research 2020-06-01
Series:Athens Journal of Health and Medical Sciences
Subjects:
Online Access:https://www.athensjournals.gr/health/2020-7-2-1-Abdullahi.pdf
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author Ibrahim Lawal Abdullahi
Ali Sani
author_facet Ibrahim Lawal Abdullahi
Ali Sani
author_sort Ibrahim Lawal Abdullahi
collection DOAJ
description Welding is described as one of the most hazardous occupations. The study aims to determine the influence of metal welding fumes on kidney function parameters in blood of the exposed animals. The fumes were collected from welding sites during the activity by a skilled welder. One hundred thirty experimental animals were used and made into 13 groups. Twelve groups were given dosages calculated to correspond to real life workers exposure regimes and 1 group served as control. The dosages were administered intratracheally after been anesthetized weekly for 12 weeks. The animals were sacrificed and whole blood samples were taken. Serum was used to determine urea, chloride (Cl), Sodium (Na), Potassium (K) and the activity of creatinkinase (CK). The values of Urea and Creatinine in the treatment groups have exceeded the control values and slightly significant. Values of electrolytes Cl, K and Na in all the treatment groups have exceeded the control. Thus, it shows impairment of the kidney by elevated serum levels of the metabolites and probable damage in the kidney function. Benchmark dose and standard limits should be proposed for such occupations in Kano.
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spelling doaj.art-23bb76fab979403d9207f58e07c94e302023-01-10T08:56:37ZengAthens Institute for Education and ResearchAthens Journal of Health and Medical Sciences2653-94112020-06-0172637410.30958/ajhms.7-2-1Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats Ibrahim Lawal Abdullahi0Ali Sani1Lecturer, Department of Biological Sciences, Bayero University, NigeriaLecturer, Department of Biological Sciences, Bayero University, NigeriaWelding is described as one of the most hazardous occupations. The study aims to determine the influence of metal welding fumes on kidney function parameters in blood of the exposed animals. The fumes were collected from welding sites during the activity by a skilled welder. One hundred thirty experimental animals were used and made into 13 groups. Twelve groups were given dosages calculated to correspond to real life workers exposure regimes and 1 group served as control. The dosages were administered intratracheally after been anesthetized weekly for 12 weeks. The animals were sacrificed and whole blood samples were taken. Serum was used to determine urea, chloride (Cl), Sodium (Na), Potassium (K) and the activity of creatinkinase (CK). The values of Urea and Creatinine in the treatment groups have exceeded the control values and slightly significant. Values of electrolytes Cl, K and Na in all the treatment groups have exceeded the control. Thus, it shows impairment of the kidney by elevated serum levels of the metabolites and probable damage in the kidney function. Benchmark dose and standard limits should be proposed for such occupations in Kano.https://www.athensjournals.gr/health/2020-7-2-1-Abdullahi.pdfeffectsevaluationkidney functionmetal welding fumes
spellingShingle Ibrahim Lawal Abdullahi
Ali Sani
Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats
Athens Journal of Health and Medical Sciences
effects
evaluation
kidney function
metal welding fumes
title Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats
title_full Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats
title_fullStr Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats
title_full_unstemmed Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats
title_short Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats
title_sort effects of metal welding fumes on kidney function parameters in male albino rats
topic effects
evaluation
kidney function
metal welding fumes
url https://www.athensjournals.gr/health/2020-7-2-1-Abdullahi.pdf
work_keys_str_mv AT ibrahimlawalabdullahi effectsofmetalweldingfumesonkidneyfunctionparametersinmalealbinorats
AT alisani effectsofmetalweldingfumesonkidneyfunctionparametersinmalealbinorats