Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats
Welding is described as one of the most hazardous occupations. The study aims to determine the influence of metal welding fumes on kidney function parameters in blood of the exposed animals. The fumes were collected from welding sites during the activity by a skilled welder. One hundred thirty exper...
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Format: | Article |
Language: | English |
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Athens Institute for Education and Research
2020-06-01
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Series: | Athens Journal of Health and Medical Sciences |
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Online Access: | https://www.athensjournals.gr/health/2020-7-2-1-Abdullahi.pdf |
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author | Ibrahim Lawal Abdullahi Ali Sani |
author_facet | Ibrahim Lawal Abdullahi Ali Sani |
author_sort | Ibrahim Lawal Abdullahi |
collection | DOAJ |
description | Welding is described as one of the most hazardous occupations. The study aims to determine the influence of metal welding fumes on kidney function parameters in blood of the exposed animals. The fumes were collected from welding sites during the activity by a skilled welder. One hundred thirty experimental animals were used and made into 13 groups. Twelve groups were given dosages calculated to correspond to real life workers exposure regimes and 1 group served as control. The dosages were administered intratracheally after been anesthetized weekly for 12 weeks. The animals were sacrificed and whole blood samples were taken. Serum was used to determine urea, chloride (Cl), Sodium (Na), Potassium (K) and the activity of creatinkinase (CK). The values of Urea and Creatinine in the treatment groups have exceeded the control values and slightly significant. Values of electrolytes Cl, K and Na in all the treatment groups have exceeded the control. Thus, it shows impairment of the kidney by elevated serum levels of the metabolites and probable damage in the kidney function. Benchmark dose and standard limits should be proposed for such occupations in Kano. |
first_indexed | 2024-04-10T23:58:38Z |
format | Article |
id | doaj.art-23bb76fab979403d9207f58e07c94e30 |
institution | Directory Open Access Journal |
issn | 2653-9411 |
language | English |
last_indexed | 2024-04-10T23:58:38Z |
publishDate | 2020-06-01 |
publisher | Athens Institute for Education and Research |
record_format | Article |
series | Athens Journal of Health and Medical Sciences |
spelling | doaj.art-23bb76fab979403d9207f58e07c94e302023-01-10T08:56:37ZengAthens Institute for Education and ResearchAthens Journal of Health and Medical Sciences2653-94112020-06-0172637410.30958/ajhms.7-2-1Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats Ibrahim Lawal Abdullahi0Ali Sani1Lecturer, Department of Biological Sciences, Bayero University, NigeriaLecturer, Department of Biological Sciences, Bayero University, NigeriaWelding is described as one of the most hazardous occupations. The study aims to determine the influence of metal welding fumes on kidney function parameters in blood of the exposed animals. The fumes were collected from welding sites during the activity by a skilled welder. One hundred thirty experimental animals were used and made into 13 groups. Twelve groups were given dosages calculated to correspond to real life workers exposure regimes and 1 group served as control. The dosages were administered intratracheally after been anesthetized weekly for 12 weeks. The animals were sacrificed and whole blood samples were taken. Serum was used to determine urea, chloride (Cl), Sodium (Na), Potassium (K) and the activity of creatinkinase (CK). The values of Urea and Creatinine in the treatment groups have exceeded the control values and slightly significant. Values of electrolytes Cl, K and Na in all the treatment groups have exceeded the control. Thus, it shows impairment of the kidney by elevated serum levels of the metabolites and probable damage in the kidney function. Benchmark dose and standard limits should be proposed for such occupations in Kano.https://www.athensjournals.gr/health/2020-7-2-1-Abdullahi.pdfeffectsevaluationkidney functionmetal welding fumes |
spellingShingle | Ibrahim Lawal Abdullahi Ali Sani Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats Athens Journal of Health and Medical Sciences effects evaluation kidney function metal welding fumes |
title | Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats |
title_full | Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats |
title_fullStr | Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats |
title_full_unstemmed | Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats |
title_short | Effects of Metal Welding Fumes on Kidney Function Parameters in Male Albino Rats |
title_sort | effects of metal welding fumes on kidney function parameters in male albino rats |
topic | effects evaluation kidney function metal welding fumes |
url | https://www.athensjournals.gr/health/2020-7-2-1-Abdullahi.pdf |
work_keys_str_mv | AT ibrahimlawalabdullahi effectsofmetalweldingfumesonkidneyfunctionparametersinmalealbinorats AT alisani effectsofmetalweldingfumesonkidneyfunctionparametersinmalealbinorats |