NxRepair: error correction in de novo sequence assembly using Nextera mate pairs

NxRepair: error correction in de novo sequence assembly using Nextera mate pairs

Scaffolding errors and incorrect repeat disambiguation during de novo assembly can result in large scale misassemblies in draft genomes. Nextera mate pair sequencing data provide additional information to resolve assembly ambiguities during scaffolding. Here, we introduce NxRepair, an open source to...

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Bibliographic Details
Main Authors: Rebecca R. Murphy, Jared O’Connell, Anthony J. Cox, Ole Schulz-Trieglaff
Format: Article
Language:English
Published: PeerJ Inc. 2015-06-01
Series:PeerJ
Subjects:
De novo assembly
Mate pair
Genome assembly
Error correction
Scaffolding
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Online Access:https://peerj.com/articles/996.pdf

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