Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds
Elements of fractal analysis are widely used in scientific research, including several biological disciplines. In this study, we hypothesized that chicken breed biodiversity manifests not only at the phenotypic level, but also at the genetic-system level in terms of different profiles of fractal con...
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MDPI AG
2023-02-01
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| Series: | Animals |
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| author | Ivan I. Kochish Evgeni A. Brazhnik Nikolai I. Vorobyov Ilya N. Nikonov Maxim V. Korenyuga Olga V. Myasnikova Darren K. Griffin Peter F. Surai Michael N. Romanov |
| author_facet | Ivan I. Kochish Evgeni A. Brazhnik Nikolai I. Vorobyov Ilya N. Nikonov Maxim V. Korenyuga Olga V. Myasnikova Darren K. Griffin Peter F. Surai Michael N. Romanov |
| author_sort | Ivan I. Kochish |
| collection | DOAJ |
| description | Elements of fractal analysis are widely used in scientific research, including several biological disciplines. In this study, we hypothesized that chicken breed biodiversity manifests not only at the phenotypic level, but also at the genetic-system level in terms of different profiles of fractal conformity and bioconsolidation in the early myogenesis gene expression. To demonstrate this effect, we developed two mathematical models that describe the fractal nature of the expression of seven key genes in the embryonic breast and thigh muscles in eight breeds of meat, dual purpose, egg and game types. In the first model, we produced breed-specific coefficients of gene expression conformity in each muscle type using the slopes of regression dependencies, as well as an integral myogenesis gene expression index (MGEI). Additionally, breed fractal dimensions and integral myogenesis gene expression fractal dimension index (MGEFDI) were determined. The second gene expression model was based on plotting fractal portraits and calculating indices of fractal bioconsolidation. The bioconsolidation index of myogenesis gene expression correlated with the chick growth rate and nitric oxide (NO) oxidation rate. The proposed fractal models were instrumental in interpreting the genetic diversity of chickens at the level of gene expression for early myogenesis, NO metabolism and the postnatal growth of chicks. |
| first_indexed | 2024-03-11T09:53:45Z |
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| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T09:53:45Z |
| publishDate | 2023-02-01 |
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| series | Animals |
| spelling | doaj.art-23bd9ab0b65e484582dfadb8d8577c3e2023-11-16T16:02:01ZengMDPI AGAnimals2076-26152023-02-0113352110.3390/ani13030521Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken BreedsIvan I. Kochish0Evgeni A. Brazhnik1Nikolai I. Vorobyov2Ilya N. Nikonov3Maxim V. Korenyuga4Olga V. Myasnikova5Darren K. Griffin6Peter F. Surai7Michael N. Romanov8K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 109472 Moscow, RussiaBIOTROF+ Ltd., Pushkin, 196602 St. Petersburg, RussiaAll-Russia Institute for Agricultural Microbiology, Pushkin, 196608 St. Petersburg, RussiaK. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 109472 Moscow, RussiaK. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 109472 Moscow, RussiaK. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 109472 Moscow, RussiaSchool of Biosciences, University of Kent, Canterbury CT2 7NJ, UKVitagene and Health Research Centre, Bristol BS4 2RS, UKK. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 109472 Moscow, RussiaElements of fractal analysis are widely used in scientific research, including several biological disciplines. In this study, we hypothesized that chicken breed biodiversity manifests not only at the phenotypic level, but also at the genetic-system level in terms of different profiles of fractal conformity and bioconsolidation in the early myogenesis gene expression. To demonstrate this effect, we developed two mathematical models that describe the fractal nature of the expression of seven key genes in the embryonic breast and thigh muscles in eight breeds of meat, dual purpose, egg and game types. In the first model, we produced breed-specific coefficients of gene expression conformity in each muscle type using the slopes of regression dependencies, as well as an integral myogenesis gene expression index (MGEI). Additionally, breed fractal dimensions and integral myogenesis gene expression fractal dimension index (MGEFDI) were determined. The second gene expression model was based on plotting fractal portraits and calculating indices of fractal bioconsolidation. The bioconsolidation index of myogenesis gene expression correlated with the chick growth rate and nitric oxide (NO) oxidation rate. The proposed fractal models were instrumental in interpreting the genetic diversity of chickens at the level of gene expression for early myogenesis, NO metabolism and the postnatal growth of chicks.https://www.mdpi.com/2076-2615/13/3/521chicken breedsgene expressionmyogenesisgenetic diversitymathematical modellingfractal analysis |
| spellingShingle | Ivan I. Kochish Evgeni A. Brazhnik Nikolai I. Vorobyov Ilya N. Nikonov Maxim V. Korenyuga Olga V. Myasnikova Darren K. Griffin Peter F. Surai Michael N. Romanov Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds Animals chicken breeds gene expression myogenesis genetic diversity mathematical modelling fractal analysis |
| title | Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds |
| title_full | Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds |
| title_fullStr | Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds |
| title_full_unstemmed | Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds |
| title_short | Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds |
| title_sort | features of fractal conformity and bioconsolidation in the early myogenesis gene expression and their relationship to the genetic diversity of chicken breeds |
| topic | chicken breeds gene expression myogenesis genetic diversity mathematical modelling fractal analysis |
| url | https://www.mdpi.com/2076-2615/13/3/521 |
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