Malignant Melanoma with Concurrent BRAF E586K and NRAS Q81K Mutations

Malignant Melanoma with Concurrent BRAF E586K and NRAS Q81K Mutations

Cutaneous melanoma is an aggressive malignant tumor of melanocytes which accounts for 80% of skin cancer-related deaths. A number of driver mutations have been identified in melanoma, with the mutually exclusive BRAF V600E and NRAS Q61A mutations together accounting for roughly 70% of mutations. Sim...

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Bibliographic Details
Main Authors: Rodney Shackelford, Maressa Pollen, Moise Vora, Tamara T. Jusion, James Cotelingam, Binu Nair
Format: Article
Language:English
Published: Karger Publishers 2014-05-01
Series:Case Reports in Oncology
Subjects:
Cutaneous melanoma
Concurrent BRAF E586K and NRAS Q81K mutations
Skin cancer
Online Access:http://www.karger.com/Article/FullText/362788

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