Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT Effective tuberculosis treatment requires at least 6 months of combination therapy. Alterations in the physiological state of the bacterium during infection are thought to reduce drug efficacy and prolong the necessary treatment period, but the nature of these adaptations remain incompletel...

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Bibliographic Details
Main Authors: Michelle M. Bellerose, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Thomas R. Ioerger, Christopher M. Sassetti
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSystems
Subjects:
antibiotic treatment
host-microbe interactions
microbial genomics
Mycobacterium tuberculosis
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00396-20

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