Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis
ABSTRACT Ovarian cancer is the leading cause of gynecological malignancy-related deaths. Current therapies for ovarian cancer do not provide meaningful and sustainable clinical benefits, highlighting the need for new therapies. We show that the histone H3K79 methyltransferase disruptor of telomeric...
Main Authors: | Suresh Chava, Suresh Bugide, Yvonne J. K. Edwards, Romi Gupta |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Oncogenesis |
Online Access: | https://doi.org/10.1038/s41389-021-00339-6 |
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