B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

Abstract B cells are important in tuberculosis (TB) immunity, but their role in the human lung is understudied. Here, we characterize B cells from lung tissue and matched blood of patients with TB and found they are decreased in the blood and increased in the lungs, consistent with recruitment to in...

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Bibliographic Details
Main Authors: Robert Krause, Paul Ogongo, Liku Tezera, Mohammed Ahmed, Ian Mbano, Mark Chambers, Abigail Ngoepe, Magalli Magnoumba, Daniel Muema, Farina Karim, Khadija Khan, Kapongo Lumamba, Kievershen Nargan, Rajhmun Madansein, Adrie Steyn, Alex K. Shalek, Paul Elkington, Al Leslie
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06282-7

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https://doi.org/10.1038/s42003-024-06282-7

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