The dark side of EGFP: defective polyubiquitination.

The dark side of EGFP: defective polyubiquitination.

Enhanced Green Fluorescent Protein (EGFP) is the most commonly used live cell reporter despite a number of conflicting reports that it can affect cell physiology. Thus far, the precise mechanism of GFP-associated defects remained unclear. Here we demonstrate that EGFP and EGFP fusion proteins inhibi...

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Bibliographic Details
Main Authors: Mathijs Baens, Heidi Noels, Vicky Broeckx, Sofie Hagens, Sabine Fevery, An D Billiau, Hugo Vankelecom, Peter Marynen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762387?pdf=render

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