Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methods
Objective To compare the quality and safety of platelet-rich plasma (PRP) by blood bag and monopheresis. Methods A retrospective analysis was performed on 66 patients treated with autologous PRP therapy in the blood transfusion department of First Affiliated Hospital of Army Medical University from...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Third Military Medical University
2022-03-01
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| Series: | Di-san junyi daxue xuebao |
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| Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/202110184.htm |
| _version_ | 1811328764199567360 |
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| author | SONG Nali WANG Shichun YI Zhongmei ZHANG Bin LIU Qi |
| author_facet | SONG Nali WANG Shichun YI Zhongmei ZHANG Bin LIU Qi |
| author_sort | SONG Nali |
| collection | DOAJ |
| description | Objective To compare the quality and safety of platelet-rich plasma (PRP) by blood bag and monopheresis. Methods A retrospective analysis was performed on 66 patients treated with autologous PRP therapy in the blood transfusion department of First Affiliated Hospital of Army Medical University from July 2019 to August 2021. According to preparation procedure, they were divided into blood bag group (n=30, with 47 times of preparation) and monopheresis group (n=36, with 36 times of preparation). The counts of erythrocytes, leukocytes and platelets and product multiples in the PRP products were detected and compared between the 2 groups. Adverse reactions were recorded and safety was evaluated. Results The preparation time, product volume, product concentration and product multiple were significantly better in the monopheresis group than the blood bag group (P < 0.01). The amount of mixed red blood cells was statistically less in the blood bag group than the apheresis group (P < 0.01). There was no notable difference in the amount of mixed white blood cells between the 2 groups. No adverse reactions were seen in both groups. Conclusion The monopheresis PRP products have higher platelets concentration than those by blood bag and need shorter time of procedure group. Therefore, monopheresis is recommended as first choice and blood bag as the alternative. |
| first_indexed | 2024-04-13T15:31:49Z |
| format | Article |
| id | doaj.art-23cc5f12427c4b84a12c17f4ef3e6b49 |
| institution | Directory Open Access Journal |
| issn | 1000-5404 |
| language | zho |
| last_indexed | 2024-04-13T15:31:49Z |
| publishDate | 2022-03-01 |
| publisher | Editorial Office of Journal of Third Military Medical University |
| record_format | Article |
| series | Di-san junyi daxue xuebao |
| spelling | doaj.art-23cc5f12427c4b84a12c17f4ef3e6b492022-12-22T02:41:22ZzhoEditorial Office of Journal of Third Military Medical UniversityDi-san junyi daxue xuebao1000-54042022-03-0144657157510.16016/j.2097-0927.202110184Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methodsSONG Nali0 WANG Shichun1YI Zhongmei2ZHANG Bin3 LIU Qi4Department of Blood Transfusion, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038Department of Blood Transfusion, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038Department of Blood Transfusion, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038Department of Blood Transfusion, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038Department of Blood Transfusion, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038Objective To compare the quality and safety of platelet-rich plasma (PRP) by blood bag and monopheresis. Methods A retrospective analysis was performed on 66 patients treated with autologous PRP therapy in the blood transfusion department of First Affiliated Hospital of Army Medical University from July 2019 to August 2021. According to preparation procedure, they were divided into blood bag group (n=30, with 47 times of preparation) and monopheresis group (n=36, with 36 times of preparation). The counts of erythrocytes, leukocytes and platelets and product multiples in the PRP products were detected and compared between the 2 groups. Adverse reactions were recorded and safety was evaluated. Results The preparation time, product volume, product concentration and product multiple were significantly better in the monopheresis group than the blood bag group (P < 0.01). The amount of mixed red blood cells was statistically less in the blood bag group than the apheresis group (P < 0.01). There was no notable difference in the amount of mixed white blood cells between the 2 groups. No adverse reactions were seen in both groups. Conclusion The monopheresis PRP products have higher platelets concentration than those by blood bag and need shorter time of procedure group. Therefore, monopheresis is recommended as first choice and blood bag as the alternative.http://aammt.tmmu.edu.cn/Upload/rhtml/202110184.htmblood bagmonopheresisautologous platelet-rich plasmablood routine examination |
| spellingShingle | SONG Nali WANG Shichun YI Zhongmei ZHANG Bin LIU Qi Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methods Di-san junyi daxue xuebao blood bag monopheresis autologous platelet-rich plasma blood routine examination |
| title | Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methods |
| title_full | Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methods |
| title_fullStr | Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methods |
| title_full_unstemmed | Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methods |
| title_short | Comparative analysis on quality and safety of autologous platelet-rich plasma collected and prepared by 2 methods |
| title_sort | comparative analysis on quality and safety of autologous platelet rich plasma collected and prepared by 2 methods |
| topic | blood bag monopheresis autologous platelet-rich plasma blood routine examination |
| url | http://aammt.tmmu.edu.cn/Upload/rhtml/202110184.htm |
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