A human circulating immune cell landscape in aging and COVID-19

A human circulating immune cell landscape in aging and COVID-19

Abstract Age-associated changes in immune cells have been linked to an increased risk for infection. However, a global and detailed characterization of the changes that human circulating immune cells undergo with age is lacking. Here, we combined scRNA-seq, mass cytometry and scATAC-seq to compare i...

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Bibliographic Details
Main Authors: Yingfeng Zheng, Xiuxing Liu, Wenqing Le, Lihui Xie, He Li, Wen Wen, Si Wang, Shuai Ma, Zhaohao Huang, Jinguo Ye, Wen Shi, Yanxia Ye, Zunpeng Liu, Moshi Song, Weiqi Zhang, Jing-Dong J. Han, Juan Carlos Izpisua Belmonte, Chuanle Xiao, Jing Qu, Hongyang Wang, Guang-Hui Liu, Wenru Su
Format: Article
Language:English
Published: Oxford University Press 2020-08-01
Series:Protein & Cell
Subjects:
aging
single-cell sequencing
blood
COVID-19
immune cells
Online Access:https://doi.org/10.1007/s13238-020-00762-2

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