Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair
Highlights Synthesis of a novel acrylate-endcapped urethane-based precursor (AUP). Physico-chemical characterization of the developed AUP material. Development of a reinforced electrospun tubular repair construct containing bioactive components. Mechanical evaluation of the repair constructs on ex v...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2022-05-01
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| Series: | Journal of Materials Science: Materials in Medicine |
| Online Access: | https://doi.org/10.1007/s10856-022-06673-4 |
| _version_ | 1818533738242375680 |
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| author | N. Pien Y. Van de Maele L. Parmentier M. Meeremans A. Mignon C. De Schauwer I. Peeters L. De Wilde A. Martens D. Mantovani S. Van Vlierberghe P. Dubruel |
| author_facet | N. Pien Y. Van de Maele L. Parmentier M. Meeremans A. Mignon C. De Schauwer I. Peeters L. De Wilde A. Martens D. Mantovani S. Van Vlierberghe P. Dubruel |
| author_sort | N. Pien |
| collection | DOAJ |
| description | Highlights Synthesis of a novel acrylate-endcapped urethane-based precursor (AUP). Physico-chemical characterization of the developed AUP material. Development of a reinforced electrospun tubular repair construct containing bioactive components. Mechanical evaluation of the repair constructs on ex vivo sheep tendons. Biological evaluation of the repair constructs by means of indirect and direct testing using mono- and co-cultures. |
| first_indexed | 2024-12-11T18:02:42Z |
| format | Article |
| id | doaj.art-23ce69eba45f4816b304f059bdfe6b31 |
| institution | Directory Open Access Journal |
| issn | 1573-4838 |
| language | English |
| last_indexed | 2024-12-11T18:02:42Z |
| publishDate | 2022-05-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Materials Science: Materials in Medicine |
| spelling | doaj.art-23ce69eba45f4816b304f059bdfe6b312022-12-22T00:55:49ZengSpringerJournal of Materials Science: Materials in Medicine1573-48382022-05-0133611710.1007/s10856-022-06673-4Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repairN. Pien0Y. Van de Maele1L. Parmentier2M. Meeremans3A. Mignon4C. De Schauwer5I. Peeters6L. De Wilde7A. Martens8D. Mantovani9S. Van Vlierberghe10P. Dubruel11Polymer Chemistry & Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Ghent UniversityPolymer Chemistry & Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Ghent UniversityPolymer Chemistry & Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Ghent UniversityFaculty of Veterinary Medicine, Department of Translational Physiology, Infectiology and Public Health, Ghent UniversitySmart Polymeric Biomaterials, Surface and Interface Engineered Materials, KU LeuvenFaculty of Veterinary Medicine, Department of Translational Physiology, Infectiology and Public Health, Ghent UniversityFaculty of Medicine and Health Sciences, Department of Human Structure and Repair, Ghent University HospitalFaculty of Medicine and Health Sciences, Department of Human Structure and Repair, Ghent University HospitalFaculty of Veterinary Medicine, Department of Large Animal Surgery, Anaesthesia and Orthopaedics, Ghent UniversityLaboratory for Biomaterials and Bioengineering, Department of Min-Met-Materials Engineering & Regenerative Medicine, CHU de Quebec Research Center, Laval UniversityPolymer Chemistry & Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Ghent UniversityPolymer Chemistry & Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Ghent UniversityHighlights Synthesis of a novel acrylate-endcapped urethane-based precursor (AUP). Physico-chemical characterization of the developed AUP material. Development of a reinforced electrospun tubular repair construct containing bioactive components. Mechanical evaluation of the repair constructs on ex vivo sheep tendons. Biological evaluation of the repair constructs by means of indirect and direct testing using mono- and co-cultures.https://doi.org/10.1007/s10856-022-06673-4 |
| spellingShingle | N. Pien Y. Van de Maele L. Parmentier M. Meeremans A. Mignon C. De Schauwer I. Peeters L. De Wilde A. Martens D. Mantovani S. Van Vlierberghe P. Dubruel Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair Journal of Materials Science: Materials in Medicine |
| title | Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair |
| title_full | Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair |
| title_fullStr | Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair |
| title_full_unstemmed | Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair |
| title_short | Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair |
| title_sort | design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair |
| url | https://doi.org/10.1007/s10856-022-06673-4 |
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