Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer

Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer

African American (AA) men have the highest incidence and mortality rate from Prostate cancer (PCa) than any other racial/ethnic group. To date, PCa genomic studies have largely under-represented tumour samples from AA men. We measured genome-wide DNA methylation in benign and tumor prostate tissues...

Full description

Bibliographic Details
Main Authors: Chad J. Creighton, Flora Zhang, Yiqun Zhang, Patricia Castro, Rong Hu, Md Islam, Somiranjan Ghosh, Michael Ittmann, Bernard Kwabi-Addo
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
clinically localized prostate cancer
dna methylation
gene expression
genome-wide profiling
cpg methylation
african american men
Online Access:http://dx.doi.org/10.1080/15592294.2023.2180585

Internet

http://dx.doi.org/10.1080/15592294.2023.2180585

Similar Items