Morphological Reconstruction of a Critical-Sized Bone Defect in the Maxillofacial Region Using Modified Chitosan in Rats with Sub-Compensated Type I Diabetes Mellitus

Morphological Reconstruction of a Critical-Sized Bone Defect in the Maxillofacial Region Using Modified Chitosan in Rats with Sub-Compensated Type I Diabetes Mellitus

It is known that complexes based on natural polysaccharides are able to eliminate bone defects. Prolonged hyperglycemia leads to low bone regeneration and a chronic inflammatory response. The purpose of this study was to increase the efficiency of early bone formation in a cavity of critical size in...

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Bibliographic Details
Main Authors: Nadezhda N. Patlataya, Igor N. Bolshakov, Vladimir A. Khorzhevskii, Anatoli A. Levenets, Nadezhda N. Medvedeva, Mariya A. Cherkashina, Matvey M. Nikolaenko, Ekaterina I. Ryaboshapko, Anna E. Dmitrienko
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Polymers
Subjects:
modified chitosan
polyelectrolyte complex CH–SA–HA rats
type I diabetes mellitus
critical-sized bone cavity
morphological reconstruction
histomorphometric criteria
Online Access:https://www.mdpi.com/2073-4360/15/21/4337

Internet

https://www.mdpi.com/2073-4360/15/21/4337

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