Association between response to anti-PD-1 treatment and blood soluble PD-L1 and IL-8 changes in patients with NSCLC

Association between response to anti-PD-1 treatment and blood soluble PD-L1 and IL-8 changes in patients with NSCLC

Abstract In this study, we explored the dynamic changes in blood sPD-L1 and its clinical value during anti-PD-1 immunotherapy in non-small cell lung cancer (NSCLC) patients. First, we established a sandwich ELISA for functional sPD-L1 that can bind to PD-1 and has biological functions. By monitoring...

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Bibliographic Details
Main Authors: Ling Yi, Xiaojue Wang, Siyun Fu, Zhuohong Yan, Tianyu Ma, Siqi Li, Panjian Wei, Hongtao Zhang, Jinghui Wang
Format: Article
Language:English
Published: Springer 2023-03-01
Series:Discover Oncology
Subjects:
NSCLC
Anti-PD-1 immunotherapy
Functional sPD-L1
IL-8
Online Access:https://doi.org/10.1007/s12672-023-00641-2

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