Cnidarian Toxins Acting on Voltage-Gated Ion Channels

Abstract: Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target volt...

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Main Authors: Robert M. Greenberg, Shanta M. Messerli
Format: Article
Language:English
Published: MDPI AG 2006-04-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/4/3/70/
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author Robert M. Greenberg
Shanta M. Messerli
author_facet Robert M. Greenberg
Shanta M. Messerli
author_sort Robert M. Greenberg
collection DOAJ
description Abstract: Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target voltage-gated ion channels, the specific channel types targeted, and, where known, the sites of action of cnidarian toxins on different channels.
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spelling doaj.art-23dfb9115c9b4b1f802c253575c490e62022-12-22T03:59:18ZengMDPI AGMarine Drugs1660-33972006-04-0143708110.3390/md403070Cnidarian Toxins Acting on Voltage-Gated Ion ChannelsRobert M. GreenbergShanta M. MesserliAbstract: Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target voltage-gated ion channels, the specific channel types targeted, and, where known, the sites of action of cnidarian toxins on different channels.http://www.mdpi.com/1660-3397/4/3/70/Cnidariaion channelstoxinsodium channelpotassium channel
spellingShingle Robert M. Greenberg
Shanta M. Messerli
Cnidarian Toxins Acting on Voltage-Gated Ion Channels
Marine Drugs
Cnidaria
ion channels
toxin
sodium channel
potassium channel
title Cnidarian Toxins Acting on Voltage-Gated Ion Channels
title_full Cnidarian Toxins Acting on Voltage-Gated Ion Channels
title_fullStr Cnidarian Toxins Acting on Voltage-Gated Ion Channels
title_full_unstemmed Cnidarian Toxins Acting on Voltage-Gated Ion Channels
title_short Cnidarian Toxins Acting on Voltage-Gated Ion Channels
title_sort cnidarian toxins acting on voltage gated ion channels
topic Cnidaria
ion channels
toxin
sodium channel
potassium channel
url http://www.mdpi.com/1660-3397/4/3/70/
work_keys_str_mv AT robertmgreenberg cnidariantoxinsactingonvoltagegatedionchannels
AT shantammesserli cnidariantoxinsactingonvoltagegatedionchannels