Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability
Pain influences plasticity within the sensorimotor system and the aim of this study was to assess the effect of pain on changes in motor performance and corticospinal excitability during training for a novel motor task. A total of 30 subjects were allocated to one of two groups (Pain, NoPain) and pe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-02-01
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| Series: | Brain Sciences |
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| Online Access: | http://www.mdpi.com/2076-3425/7/2/15 |
| _version_ | 1818006992498720768 |
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| author | Nicolas Mavromatis Cécilia Neige Martin Gagné Karen T. Reilly Catherine Mercier |
| author_facet | Nicolas Mavromatis Cécilia Neige Martin Gagné Karen T. Reilly Catherine Mercier |
| author_sort | Nicolas Mavromatis |
| collection | DOAJ |
| description | Pain influences plasticity within the sensorimotor system and the aim of this study was to assess the effect of pain on changes in motor performance and corticospinal excitability during training for a novel motor task. A total of 30 subjects were allocated to one of two groups (Pain, NoPain) and performed ten training blocks of a visually-guided isometric pinch task. Each block consisted of 15 force sequences, and subjects modulated the force applied to a transducer in order to reach one of five target forces. Pain was induced by applying capsaicin cream to the thumb. Motor performance was assessed by a skill index that measured shifts in the speed–accuracy trade-off function. Neurophysiological measures were taken from the first dorsal interosseous using transcranial magnetic stimulation. Overall, the Pain group performed better throughout the training (p = 0.03), but both groups showed similar improvements across training blocks (p < 0.001), and there was no significant interaction. Corticospinal excitability in the NoPain group increased halfway through the training, but this was not observed in the Pain group (Time × Group interaction; p = 0.01). These results suggest that, even when pain does not negatively impact on the acquisition of a novel motor task, it can affect training-related changes in corticospinal excitability. |
| first_indexed | 2024-04-14T05:08:06Z |
| format | Article |
| id | doaj.art-23dff4b726484ac1bd9784d521007d66 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-04-14T05:08:06Z |
| publishDate | 2017-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-23dff4b726484ac1bd9784d521007d662022-12-22T02:10:37ZengMDPI AGBrain Sciences2076-34252017-02-01721510.3390/brainsci7020015brainsci7020015Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal ExcitabilityNicolas Mavromatis0Cécilia Neige1Martin Gagné2Karen T. Reilly3Catherine Mercier4Center for Interdisciplinary Research in Rehabilitation and Social Integration, Québec, QC G1M 2S8, CanadaCenter for Interdisciplinary Research in Rehabilitation and Social Integration, Québec, QC G1M 2S8, CanadaCenter for Interdisciplinary Research in Rehabilitation and Social Integration, Québec, QC G1M 2S8, CanadaImpAct Team, Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Bron 69500, FranceCenter for Interdisciplinary Research in Rehabilitation and Social Integration, Québec, QC G1M 2S8, CanadaPain influences plasticity within the sensorimotor system and the aim of this study was to assess the effect of pain on changes in motor performance and corticospinal excitability during training for a novel motor task. A total of 30 subjects were allocated to one of two groups (Pain, NoPain) and performed ten training blocks of a visually-guided isometric pinch task. Each block consisted of 15 force sequences, and subjects modulated the force applied to a transducer in order to reach one of five target forces. Pain was induced by applying capsaicin cream to the thumb. Motor performance was assessed by a skill index that measured shifts in the speed–accuracy trade-off function. Neurophysiological measures were taken from the first dorsal interosseous using transcranial magnetic stimulation. Overall, the Pain group performed better throughout the training (p = 0.03), but both groups showed similar improvements across training blocks (p < 0.001), and there was no significant interaction. Corticospinal excitability in the NoPain group increased halfway through the training, but this was not observed in the Pain group (Time × Group interaction; p = 0.01). These results suggest that, even when pain does not negatively impact on the acquisition of a novel motor task, it can affect training-related changes in corticospinal excitability.http://www.mdpi.com/2076-3425/7/2/15transcranial magnetic stimulationmotor cortexmotor acquisitionmotor learningplasticity |
| spellingShingle | Nicolas Mavromatis Cécilia Neige Martin Gagné Karen T. Reilly Catherine Mercier Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability Brain Sciences transcranial magnetic stimulation motor cortex motor acquisition motor learning plasticity |
| title | Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability |
| title_full | Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability |
| title_fullStr | Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability |
| title_full_unstemmed | Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability |
| title_short | Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability |
| title_sort | effect of experimental hand pain on training induced changes in motor performance and corticospinal excitability |
| topic | transcranial magnetic stimulation motor cortex motor acquisition motor learning plasticity |
| url | http://www.mdpi.com/2076-3425/7/2/15 |
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