Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite Nanoparticles
Abstract Applications in biomedicine and ferrofluids, for instance, require long‐term colloidally stable, concentrated aqueous dispersions of magnetic, biocompatible nanoparticles. Iron oxide and related spinel ferrite nanoparticles stabilized with organic molecules allow fine‐tuning of magnetic pro...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2020-11-01
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| Series: | ChemistryOpen |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/open.202000313 |
| _version_ | 1818027849696673792 |
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| author | Mirco Eckardt Sabrina L. J. Thomä Dr. Martin Dulle Dr. Gerald Hörner Prof. Birgit Weber Prof. Stefan Förster Prof. Mirijam Zobel |
| author_facet | Mirco Eckardt Sabrina L. J. Thomä Dr. Martin Dulle Dr. Gerald Hörner Prof. Birgit Weber Prof. Stefan Förster Prof. Mirijam Zobel |
| author_sort | Mirco Eckardt |
| collection | DOAJ |
| description | Abstract Applications in biomedicine and ferrofluids, for instance, require long‐term colloidally stable, concentrated aqueous dispersions of magnetic, biocompatible nanoparticles. Iron oxide and related spinel ferrite nanoparticles stabilized with organic molecules allow fine‐tuning of magnetic properties via cation substitution and water‐dispersibility. Here, we synthesize≤5 nm iron oxide and spinel ferrite nanoparticles, capped with citrate, betaine and phosphocholine, in a one‐pot strategy. We present a robust approach combining elemental (CHN) and thermal gravimetric analysis (TGA) to quantify the ratio of residual solvent molecules and organic stabilizers on the particle surface, being of particular accuracy for ligands with heteroatoms compared to the solvent. SAXS experiments demonstrate the long‐term colloidal stability of our aqueous iron oxide and spinel ferrite nanoparticle dispersions for at least 3 months. By the use of SAXS we approved directly the colloidal stability of the nanoparticle dispersions for high concentrations up to 100 g L−1. |
| first_indexed | 2024-12-10T04:54:26Z |
| format | Article |
| id | doaj.art-23e10bba032f4521a030c4780283a7fe |
| institution | Directory Open Access Journal |
| issn | 2191-1363 |
| language | English |
| last_indexed | 2024-12-10T04:54:26Z |
| publishDate | 2020-11-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | ChemistryOpen |
| spelling | doaj.art-23e10bba032f4521a030c4780283a7fe2022-12-22T02:01:31ZengWiley-VCHChemistryOpen2191-13632020-11-019111214122010.1002/open.202000313Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite NanoparticlesMirco Eckardt0Sabrina L. J. Thomä1Dr. Martin Dulle2Dr. Gerald Hörner3Prof. Birgit Weber4Prof. Stefan Förster5Prof. Mirijam Zobel6Department of Chemistry University of Bayreuth Universitätsstr.30 95440 Bayreuth GermanyDepartment of Chemistry University of Bayreuth Universitätsstr.30 95440 Bayreuth GermanyJCNS-1/IBI-8: Neutron Scattering and Biological Matter Forschungszentrum Jülich Gmbh Wilhelm-Johnen-Straße 52428 Jülich GermanyDepartment of Chemistry University of Bayreuth Universitätsstr.30 95440 Bayreuth GermanyDepartment of Chemistry University of Bayreuth Universitätsstr.30 95440 Bayreuth GermanyJCNS-1/IBI-8: Neutron Scattering and Biological Matter Forschungszentrum Jülich Gmbh Wilhelm-Johnen-Straße 52428 Jülich GermanyDepartment of Chemistry University of Bayreuth Universitätsstr.30 95440 Bayreuth GermanyAbstract Applications in biomedicine and ferrofluids, for instance, require long‐term colloidally stable, concentrated aqueous dispersions of magnetic, biocompatible nanoparticles. Iron oxide and related spinel ferrite nanoparticles stabilized with organic molecules allow fine‐tuning of magnetic properties via cation substitution and water‐dispersibility. Here, we synthesize≤5 nm iron oxide and spinel ferrite nanoparticles, capped with citrate, betaine and phosphocholine, in a one‐pot strategy. We present a robust approach combining elemental (CHN) and thermal gravimetric analysis (TGA) to quantify the ratio of residual solvent molecules and organic stabilizers on the particle surface, being of particular accuracy for ligands with heteroatoms compared to the solvent. SAXS experiments demonstrate the long‐term colloidal stability of our aqueous iron oxide and spinel ferrite nanoparticle dispersions for at least 3 months. By the use of SAXS we approved directly the colloidal stability of the nanoparticle dispersions for high concentrations up to 100 g L−1.https://doi.org/10.1002/open.202000313colloidal stabilitynanoparticlesspinel phaseSAXSferrites |
| spellingShingle | Mirco Eckardt Sabrina L. J. Thomä Dr. Martin Dulle Dr. Gerald Hörner Prof. Birgit Weber Prof. Stefan Förster Prof. Mirijam Zobel Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite Nanoparticles ChemistryOpen colloidal stability nanoparticles spinel phase SAXS ferrites |
| title | Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite Nanoparticles |
| title_full | Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite Nanoparticles |
| title_fullStr | Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite Nanoparticles |
| title_full_unstemmed | Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite Nanoparticles |
| title_short | Long‐Term Colloidally Stable Aqueous Dispersions of ≤5 nm Spinel Ferrite Nanoparticles |
| title_sort | long term colloidally stable aqueous dispersions of ≤5 nm spinel ferrite nanoparticles |
| topic | colloidal stability nanoparticles spinel phase SAXS ferrites |
| url | https://doi.org/10.1002/open.202000313 |
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