Whole-Genome Sequencing as Tool for Investigating International Tuberculosis Outbreaks: A Systematic Review

Whole-Genome Sequencing as Tool for Investigating International Tuberculosis Outbreaks: A Systematic Review

Background: Whole-genome sequencing (WGS) can support the investigation of tuberculosis (TB) outbreaks. The technique has been applied to estimate the timing and directionality of transmission and to exclude cases from an investigation. This review assesses how WGS was applied in international outbr...

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Bibliographic Details
Main Authors: Marieke J. van der Werf, Csaba Ködmön
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Public Health
Subjects:
whole-genome sequencing
outbreak
tuberculosis
multicountry
international
cluster
Online Access:https://www.frontiersin.org/article/10.3389/fpubh.2019.00087/full

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