Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual association

Few cases of AIDS associated to manifestations suggesting Behçet's syndrome have been reported. This case is of a young married woman who presented, during a period of 7 years, clinical manifestations consistent with the late diagnosis of Behçet's syndrome, when she developed recurrent lym...

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Main Authors: Wiliam Habib Chahade, Virgina de Faria Soares, Thais Guimarães, Suzi Osana Teixeira Berbert, Isac Szarf Szwarc, Guido Carlos Levi
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801994000300003&lng=en&tlng=en
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author Wiliam Habib Chahade
Virgina de Faria Soares
Thais Guimarães
Suzi Osana Teixeira Berbert
Isac Szarf Szwarc
Guido Carlos Levi
author_facet Wiliam Habib Chahade
Virgina de Faria Soares
Thais Guimarães
Suzi Osana Teixeira Berbert
Isac Szarf Szwarc
Guido Carlos Levi
author_sort Wiliam Habib Chahade
collection DOAJ
description Few cases of AIDS associated to manifestations suggesting Behçet's syndrome have been reported. This case is of a young married woman who presented, during a period of 7 years, clinical manifestations consistent with the late diagnosis of Behçet's syndrome, when she developed recurrent lymphomonocytic meningoencephalitis. At this time, she was found to be infected by HIV-1. Immunosupressive doses of glucocorticoid produced an unsatisfactory response and she evolved to death due to CNS toxoplasmosis. The latter diagnosis was presumed on the basis of magnetic resonance imaging findings and proved by necropsy after her third hospital stay. One of the factors hindering the appropriate diagnosis was the low level of CD4 and the CD4/CD8 ratio, sometimes observed in active Behçet's syndrome and higher than those observed in patients with this severe opportunistic infection. No information about the exact period of time she had been infected with HIV-1 is available. So, we do not know whether both diseases were overlor, if the patient, infected by HIV-1, developed an unusual clinical feature consistent with Behçet's Behçet's syndrome, and subsequently evolved to AIDS.
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spelling doaj.art-23e4a6e0b9da4c6e9305b91fc5eb28dd2022-12-21T18:51:00ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-9460112358759010.1590/S1516-31801994000300003S1516-31801994000300003Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual associationWiliam Habib Chahade0Virgina de Faria Soares1Thais Guimarães2Suzi Osana Teixeira Berbert3Isac Szarf Szwarc4Guido Carlos Levi5Hospital do Servidor Público Estadual Francisco Morato de OliveiraHospital do Servidor Público Estadual Francisco Morato de OliveiraHospital do Servidor Público Estadual Francisco Morato de OliveiraHospital do Servidor Público Estadual Francisco Morato de OliveiraHospital do Servidor Público Estadual Francisco Morato de OliveiraHospital do Servidor Público Estadual Francisco Morato de OliveiraFew cases of AIDS associated to manifestations suggesting Behçet's syndrome have been reported. This case is of a young married woman who presented, during a period of 7 years, clinical manifestations consistent with the late diagnosis of Behçet's syndrome, when she developed recurrent lymphomonocytic meningoencephalitis. At this time, she was found to be infected by HIV-1. Immunosupressive doses of glucocorticoid produced an unsatisfactory response and she evolved to death due to CNS toxoplasmosis. The latter diagnosis was presumed on the basis of magnetic resonance imaging findings and proved by necropsy after her third hospital stay. One of the factors hindering the appropriate diagnosis was the low level of CD4 and the CD4/CD8 ratio, sometimes observed in active Behçet's syndrome and higher than those observed in patients with this severe opportunistic infection. No information about the exact period of time she had been infected with HIV-1 is available. So, we do not know whether both diseases were overlor, if the patient, infected by HIV-1, developed an unusual clinical feature consistent with Behçet's Behçet's syndrome, and subsequently evolved to AIDS.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801994000300003&lng=en&tlng=enAids Behçet's Syndrome Cerebral toxoplasmosis
spellingShingle Wiliam Habib Chahade
Virgina de Faria Soares
Thais Guimarães
Suzi Osana Teixeira Berbert
Isac Szarf Szwarc
Guido Carlos Levi
Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual association
São Paulo Medical Journal
Aids Behçet's Syndrome Cerebral toxoplasmosis
title Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual association
title_full Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual association
title_fullStr Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual association
title_full_unstemmed Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual association
title_short Behçet's syndrome / AIDS / cerebral toxoplasmosis: an unusual association
title_sort behcet s syndrome aids cerebral toxoplasmosis an unusual association
topic Aids Behçet's Syndrome Cerebral toxoplasmosis
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801994000300003&lng=en&tlng=en
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