COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents

COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents

The dopaminergic system has been shown to have substantial effects on the etiology of attention-deficit hyperactivity disorder (ADHD). However, while some studies found a significant direct effect, others did not. In this context, social behavior might play an important role as a factor that is rela...

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Main Authors: Sabina K. Millenet, Frauke Nees, Stefan Heintz, Christiane Bach, Josef Frank, Sabine Vollstädt-Klein, Arun Bokde, Uli Bromberg, Christian Büchel, Erin B. Quinlan, Sylvane Desrivières, Juliane Fröhner, Herta Flor, Vincent Frouin, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Herve Lemaire, Jean-Luc Martinot, Marie-Laure P. Martinot, Dimitri O. Papadoulos, Tomáš Paus, Luise Poustka, Marcella Rietschel, Michael N. Smolka, Henrik Walter, Rob Whelan, Gunter Schumann, Tobias Banaschewski, Sarah Hohmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Genetics
Subjects:
ADHD
COMT
social impairment
adolescence
moderation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00284/full

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