Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally

Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally

Abstract Background The amygdala controls socioemotional behavior and has consistently been implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala development is commonly reported in ASD youth with the degree of overgrowth positively correlated to the severity of ASD sympt...

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Hlavní autoři: Catherine E. Barrett, Thomas M. Hennessey, Katelyn M. Gordon, Steve J. Ryan, Morgan L. McNair, Kerry J. Ressler, Donald G. Rainnie
Médium: Článek
Jazyk:English
Vydáno: BMC 2017-08-01
Edice:Molecular Autism
Témata:
Valproic acid
Autism
Social behavior
Basolateral amygdala
Protein kinase A
Transcriptomics
On-line přístup:http://link.springer.com/article/10.1186/s13229-017-0160-x

Internet

http://link.springer.com/article/10.1186/s13229-017-0160-x

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