Comparison of immunogenicity and safety outcomes of a malaria vaccine FMP013/ALFQ in rhesus macaques (Macaca mulatta) of Indian and Chinese origin

Comparison of immunogenicity and safety outcomes of a malaria vaccine FMP013/ALFQ in rhesus macaques (Macaca mulatta) of Indian and Chinese origin

Abstract Background Indian-origin rhesus (InR) are preferred for research, but strict export restrictions continue to limit their use. Chinese-origin rhesus (ChR), although easier to procure, are genetically distinct from InR and differ in their immune response to infectious agents, such as the Simi...

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Bibliographic Details
Main Authors: Monica L. Martin, Alexis A. Bitzer, Andrew Schrader, Elke S. Bergmann-Leitner, Kim Soto, Xiaoyan Zou, Zoltan Beck, Gary R. Matyas, Sheetij Dutta
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Malaria Journal
Subjects:
Circumsporozoite protein
CSP
Rhesus
Chinese origin
Indian origin
Macaque
Online Access:http://link.springer.com/article/10.1186/s12936-019-3014-5

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