Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging
Magnesium (Mg)-based implants have re-emerged in orthopaedic surgery as an alternative to permanent implants. Literature reveals little information on how the degradation of biodegradable implants may introduce safety implications for patient follow-up using medical imaging. Magnetic resonance imagi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2023-07-01
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| Series: | Bioactive Materials |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X23000294 |
| _version_ | 1797861065851142144 |
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| author | Jonathan Espiritu Mostafa Berangi Hanna Cwieka Kamila Iskhakova Andre Kuehne D.C. Florian Wieland Berit Zeller-Plumhoff Thoralf Niendorf Regine Willumeit-Römer Jan-Marten Seitz |
| author_facet | Jonathan Espiritu Mostafa Berangi Hanna Cwieka Kamila Iskhakova Andre Kuehne D.C. Florian Wieland Berit Zeller-Plumhoff Thoralf Niendorf Regine Willumeit-Römer Jan-Marten Seitz |
| author_sort | Jonathan Espiritu |
| collection | DOAJ |
| description | Magnesium (Mg)-based implants have re-emerged in orthopaedic surgery as an alternative to permanent implants. Literature reveals little information on how the degradation of biodegradable implants may introduce safety implications for patient follow-up using medical imaging. Magnetic resonance imaging (MRI) benefits post-surgery monitoring of bone healing and implantation sites. Previous studies demonstrated radiofrequency (RF) heating of permanent implants caused by electromagnetic fields used in MRI. Our investigation is the first to report the effect of the degradation layer on RF-induced heating of biodegradable orthopaedic implants.WE43 orthopaedic compression screws underwent in vitro degradation. Imaging techniques were applied to assess the corrosion process and the material composition of the degraded screws. Temperature measurements were performed to quantify implant heating with respect to the degradation layer. For comparison, a commercial titanium implant screw was used.Strongest RF induced heating was observed for non-degraded WE43 screw samples. Implant heating had shown to decrease with the formation of the degradation layer. No statistical differences were observed for heating of the non-degraded WE43 material and the titanium equivalent. The highest risk of implant RF heating is most pronounced for Mg-based screws prior to degradation. Amendment to industry standards for MRI safety assessment is warranted to include biodegradable materials. |
| first_indexed | 2024-04-09T21:56:04Z |
| format | Article |
| id | doaj.art-23ec447e3c634c98867c7bba6ce8c735 |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-09T21:56:04Z |
| publishDate | 2023-07-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-23ec447e3c634c98867c7bba6ce8c7352023-03-24T04:23:08ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2023-07-01258694Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imagingJonathan Espiritu0Mostafa Berangi1Hanna Cwieka2Kamila Iskhakova3Andre Kuehne4D.C. Florian Wieland5Berit Zeller-Plumhoff6Thoralf Niendorf7Regine Willumeit-Römer8Jan-Marten Seitz9Syntellix AG, Hannover, Germany; Corresponding author.MRI.TOOLS GmbH, Berlin, Germany; Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GermanyInstitute of Metallic Biomaterials, Helmholtz Zentrum Hereon, Geesthacht, GermanyInstitute of Metallic Biomaterials, Helmholtz Zentrum Hereon, Geesthacht, GermanyMRI.TOOLS GmbH, Berlin, GermanyInstitute of Metallic Biomaterials, Helmholtz Zentrum Hereon, Geesthacht, GermanyInstitute of Metallic Biomaterials, Helmholtz Zentrum Hereon, Geesthacht, GermanyMRI.TOOLS GmbH, Berlin, Germany; Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GermanyInstitute of Metallic Biomaterials, Helmholtz Zentrum Hereon, Geesthacht, GermanySyntellix AG, Hannover, GermanyMagnesium (Mg)-based implants have re-emerged in orthopaedic surgery as an alternative to permanent implants. Literature reveals little information on how the degradation of biodegradable implants may introduce safety implications for patient follow-up using medical imaging. Magnetic resonance imaging (MRI) benefits post-surgery monitoring of bone healing and implantation sites. Previous studies demonstrated radiofrequency (RF) heating of permanent implants caused by electromagnetic fields used in MRI. Our investigation is the first to report the effect of the degradation layer on RF-induced heating of biodegradable orthopaedic implants.WE43 orthopaedic compression screws underwent in vitro degradation. Imaging techniques were applied to assess the corrosion process and the material composition of the degraded screws. Temperature measurements were performed to quantify implant heating with respect to the degradation layer. For comparison, a commercial titanium implant screw was used.Strongest RF induced heating was observed for non-degraded WE43 screw samples. Implant heating had shown to decrease with the formation of the degradation layer. No statistical differences were observed for heating of the non-degraded WE43 material and the titanium equivalent. The highest risk of implant RF heating is most pronounced for Mg-based screws prior to degradation. Amendment to industry standards for MRI safety assessment is warranted to include biodegradable materials.http://www.sciencedirect.com/science/article/pii/S2452199X23000294Biodegradable implantsMagnesiumMedical imagingMagnetic resonance imagingPatient safety |
| spellingShingle | Jonathan Espiritu Mostafa Berangi Hanna Cwieka Kamila Iskhakova Andre Kuehne D.C. Florian Wieland Berit Zeller-Plumhoff Thoralf Niendorf Regine Willumeit-Römer Jan-Marten Seitz Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging Bioactive Materials Biodegradable implants Magnesium Medical imaging Magnetic resonance imaging Patient safety |
| title | Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging |
| title_full | Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging |
| title_fullStr | Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging |
| title_full_unstemmed | Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging |
| title_short | Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging |
| title_sort | radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging |
| topic | Biodegradable implants Magnesium Medical imaging Magnetic resonance imaging Patient safety |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X23000294 |
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