The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
MiR-4295, located on chromosome 10q25.2, is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed in vivo, participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in various cancers, it has also been found to have the function...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2022-05-01
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| Series: | Genes and Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352304220301252 |
| _version_ | 1797763474993971200 |
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| author | Yin Li Yihan Zhang Yuhao Zou Shiwei Duan |
| author_facet | Yin Li Yihan Zhang Yuhao Zou Shiwei Duan |
| author_sort | Yin Li |
| collection | DOAJ |
| description | MiR-4295, located on chromosome 10q25.2, is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed in vivo, participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in various cancers, it has also been found to have the function of inhibiting cancer. At the same time, the expression of miR-4295 is related to prognosis and can be affected by numerous factors connecting to the therapeutic effects of various drugs. This article is to better summarize the role of miR-4295 in cancer and review the potential diagnostic, prognostic, and therapeutic value of miR-4295, which may provide insight into subsequent research. |
| first_indexed | 2024-03-12T19:43:01Z |
| format | Article |
| id | doaj.art-23ede233457d49b48109eb5ccdbc4843 |
| institution | Directory Open Access Journal |
| issn | 2352-3042 |
| language | English |
| last_indexed | 2024-03-12T19:43:01Z |
| publishDate | 2022-05-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Genes and Diseases |
| spelling | doaj.art-23ede233457d49b48109eb5ccdbc48432023-08-02T03:43:18ZengKeAi Communications Co., Ltd.Genes and Diseases2352-30422022-05-0193638647The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicineYin Li0Yihan Zhang1Yuhao Zou2Shiwei Duan3Medical Genetics Center, Ningbo University School of Medicine, Ningbo, Zhejiang 315211, PR ChinaMedical Genetics Center, Ningbo University School of Medicine, Ningbo, Zhejiang 315211, PR ChinaMedical Genetics Center, Ningbo University School of Medicine, Ningbo, Zhejiang 315211, PR ChinaCorresponding author.; Medical Genetics Center, Ningbo University School of Medicine, Ningbo, Zhejiang 315211, PR ChinaMiR-4295, located on chromosome 10q25.2, is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed in vivo, participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in various cancers, it has also been found to have the function of inhibiting cancer. At the same time, the expression of miR-4295 is related to prognosis and can be affected by numerous factors connecting to the therapeutic effects of various drugs. This article is to better summarize the role of miR-4295 in cancer and review the potential diagnostic, prognostic, and therapeutic value of miR-4295, which may provide insight into subsequent research.http://www.sciencedirect.com/science/article/pii/S2352304220301252CancerCancer cellsmiR-4295Molecular functionPrognosisTumor suppressor |
| spellingShingle | Yin Li Yihan Zhang Yuhao Zou Shiwei Duan The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine Genes and Diseases Cancer Cancer cells miR-4295 Molecular function Prognosis Tumor suppressor |
| title | The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine |
| title_full | The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine |
| title_fullStr | The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine |
| title_full_unstemmed | The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine |
| title_short | The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine |
| title_sort | paradoxical roles of mir 4295 in human cancer implications in pathogenesis and personalized medicine |
| topic | Cancer Cancer cells miR-4295 Molecular function Prognosis Tumor suppressor |
| url | http://www.sciencedirect.com/science/article/pii/S2352304220301252 |
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