Dexamethasone Treatment Limits Efficacy of Radiation, but Does Not Interfere With Glioma Cell Death Induced by Tumor Treating Fields

Dexamethasone Treatment Limits Efficacy of Radiation, but Does Not Interfere With Glioma Cell Death Induced by Tumor Treating Fields

PurposeDexamethasone (Dex) is the most common corticosteroid to treat edema in glioblastoma (GBM) patients. Recent studies identified the addition of Dex to radiation therapy (RT) to be associated with poor survival. Independently, Tumor Treating Fields (TTFields) provides a novel anti-cancer modali...

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Bibliographic Details
Main Authors: Benedikt Linder, Abigail Schiesl, Martin Voss, Franz Rödel, Stephanie Hehlgans, Ömer Güllülü, Volker Seifert, Donat Kögel, Christian Senft, Daniel Dubinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
brain cancer
TTFields
corticosteroids
dexamethasone
glioma
survival
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.715031/full

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