Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development
Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite d...
| मुख्य लेखकों: | , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Nature Portfolio
2019-12-01
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| श्रृंखला: | Nature Communications |
| ऑनलाइन पहुंच: | https://doi.org/10.1038/s41467-019-13627-y |
| _version_ | 1831581023223152640 |
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| author | Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina |
| author_facet | Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina |
| author_sort | Lena Lampe |
| collection | DOAJ |
| description | Plasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development. |
| first_indexed | 2024-12-17T16:56:23Z |
| format | Article |
| id | doaj.art-23f1a323f4ee4ef29a1a1b5a9d1e81c3 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T16:56:23Z |
| publishDate | 2019-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-23f1a323f4ee4ef29a1a1b5a9d1e81c32022-12-21T21:40:26ZengNature PortfolioNature Communications2041-17232019-12-0110111010.1038/s41467-019-13627-yMetabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum developmentLena Lampe0Marius Jentzsch1Sylwia Kierszniowska2Elena A. Levashina3Vector Biology Unit, Max Planck Institute for Infection BiologyVector Biology Unit, Max Planck Institute for Infection BiologymetaSysX GmbHVector Biology Unit, Max Planck Institute for Infection BiologyPlasmodium growth is adapted to the reproductive cycle of mosquitoes, but underlying mechanisms are unclear. Here, Lampe et al. show that the blood-meal induced miR-276 balances the termination of the mosquito amino acid catabolism and egg development, providing nutrients for Plasmodium sporozoite development.https://doi.org/10.1038/s41467-019-13627-y |
| spellingShingle | Lena Lampe Marius Jentzsch Sylwia Kierszniowska Elena A. Levashina Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development Nature Communications |
| title | Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
| title_full | Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
| title_fullStr | Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
| title_full_unstemmed | Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
| title_short | Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development |
| title_sort | metabolic balancing by mir 276 shapes the mosquito reproductive cycle and plasmodium falciparum development |
| url | https://doi.org/10.1038/s41467-019-13627-y |
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