Overexpression of PLXDC2 in Stromal Cell-Associated M2 Macrophages Is Related to EMT and the Progression of Gastric Cancer

Overexpression of PLXDC2 in Stromal Cell-Associated M2 Macrophages Is Related to EMT and the Progression of Gastric Cancer

The tumor microenvironment (TME) comprises distinct cell types, including stromal types such as fibroblast cells and macrophage cells, which have recently become a critical factor in tumor development and progression. Here, we identified the TME-related gene, plexin domain containing 2 (PLXDC2), in...

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Bibliographic Details
Main Authors: Yiming Guan, Yuzhang Du, Guanzheng Wang, Hongquan Gou, Yilun Xue, Jingsong Xu, Enhao Li, David W. Chan, Di Wu, Peiqing Xu, Peihua Ni, Dakang Xu, Yiqun Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tumor-associated M2 macrophages
gastric cancer
plexin domain containing 2 (PLXDC2)
stroma
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.673295/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.673295/full

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