Monocyte-derived Kupffer cells dominate in the Kupffer cell pool during liver injury

Monocyte-derived Kupffer cells dominate in the Kupffer cell pool during liver injury

Summary: Healthy Kupffer cell (KC) pool is dominated by embryonic KCs (EmKCs), preserving liver homeostasis. How the KC pool varies upon injury remains unclear. Using chimeric mice with bone marrow (BM) cells labeled with enhanced green fluorescent protein, we identify that BM monocyte-derived KCs (...

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Bibliographic Details
Main Authors: Weiyang Li, Yuanru Yang, Lin Yang, Na Chang, Liying Li
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Reports
Subjects:
CP: Immunology
Cell Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723011762

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