Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions

Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions

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A number of neurologic diseases associated with expanded nucleotide repeats, including an inherited form of amyotrophic lateral sclerosis, have an unconventional form of translation called repeat-associated non-AUG (RAN) translation. It has been speculated that the repeat regions in the RNA fold int...

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Bibliographic Details
Main Authors: Alec C. Gleason, Ghanashyam Ghadge, Jin Chen, Yoshifumi Sonobe, Raymond P. Roos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159584/?tool=EBI

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