Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure
The mineralocorticoid receptor antagonists spironolactone and eplerenone have become part of standard medical therapy for heart failure (HF). Randomized clinical trials have shown the clinical efficacy of spironolactone and eplerenone, which lead to lower death rates in patients with systolic HF. Wh...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2013-12-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31414 |
| _version_ | 1818400856934973440 |
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| author | S N Tereshchenko I V Zhirov Iu F Osmolovskaia |
| author_facet | S N Tereshchenko I V Zhirov Iu F Osmolovskaia |
| author_sort | S N Tereshchenko |
| collection | DOAJ |
| description | The mineralocorticoid receptor antagonists spironolactone and eplerenone have become part of standard medical therapy for heart failure (HF). Randomized clinical trials have shown the clinical efficacy of spironolactone and eplerenone, which lead to lower death rates in patients with systolic HF. Whether these two drugs are equivalent and able to exert a positive effect in patients with clinical HF, including chronic HF with retained left ventricular systolic function remains to be answered. |
| first_indexed | 2024-12-14T07:43:14Z |
| format | Article |
| id | doaj.art-23ff308493c14226bc0228fc8f94dd24 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-14T07:43:14Z |
| publishDate | 2013-12-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-23ff308493c14226bc0228fc8f94dd242022-12-21T23:10:57Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422013-12-01851213714328430Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failureS N TereshchenkoI V ZhirovIu F OsmolovskaiaThe mineralocorticoid receptor antagonists spironolactone and eplerenone have become part of standard medical therapy for heart failure (HF). Randomized clinical trials have shown the clinical efficacy of spironolactone and eplerenone, which lead to lower death rates in patients with systolic HF. Whether these two drugs are equivalent and able to exert a positive effect in patients with clinical HF, including chronic HF with retained left ventricular systolic function remains to be answered.https://ter-arkhiv.ru/0040-3660/article/view/31414aldosteronemineralocorticoid receptor antagonistschronic heart failure |
| spellingShingle | S N Tereshchenko I V Zhirov Iu F Osmolovskaia Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure Терапевтический архив aldosterone mineralocorticoid receptor antagonists chronic heart failure |
| title | Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure |
| title_full | Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure |
| title_fullStr | Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure |
| title_full_unstemmed | Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure |
| title_short | Mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure |
| title_sort | mineralocorticoid receptor antagonists in the treatment of patients with heart failure after myocardial infarction and those with chronic heart failure |
| topic | aldosterone mineralocorticoid receptor antagonists chronic heart failure |
| url | https://ter-arkhiv.ru/0040-3660/article/view/31414 |
| work_keys_str_mv | AT sntereshchenko mineralocorticoidreceptorantagonistsinthetreatmentofpatientswithheartfailureaftermyocardialinfarctionandthosewithchronicheartfailure AT ivzhirov mineralocorticoidreceptorantagonistsinthetreatmentofpatientswithheartfailureaftermyocardialinfarctionandthosewithchronicheartfailure AT iufosmolovskaia mineralocorticoidreceptorantagonistsinthetreatmentofpatientswithheartfailureaftermyocardialinfarctionandthosewithchronicheartfailure |