Dysequilibrium of the PTH-FGF23-vitamin D axis in relapsing remitting multiple sclerosis; a longitudinal study

Dysequilibrium of the PTH-FGF23-vitamin D axis in relapsing remitting multiple sclerosis; a longitudinal study

Abstract Background Parathyroid glands of people with relapsing remitting multiple sclerosis (RRMS) fail to respond to low serum 25-hydroxyvitamin D (25OHD) and low serum calcium, which are stimuli for parathyroid hormone (PTH) secretion. This led us to hypothesise: that there is suppression of PTH...

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Bibliographic Details
Main Authors: Mark Simon Stein, Gregory John Ward, Helmut Butzkueven, Trevor John Kilpatrick, Leonard Charles Harrison
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Molecular Medicine
Subjects:
Multiple sclerosis
Vitamin D
Parathyroid hormone
Fibroblast growth factor 23
Online Access:http://link.springer.com/article/10.1186/s10020-018-0028-3

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