Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series study
Background: The right ventricular outflow tract (RVOT) palliation has been shown to be a proper interventional procedure for lowering risk of mortality and improving clinical condition in cyanotic congenital heart disease (CHD) patients. Objectives: The present study aimed to assess the consequences...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Research in Cardiovascular Medicine |
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| Online Access: | http://www.rcvmonline.com/article.asp?issn=2251-9572;year=2016;volume=5;issue=3;spage=4;epage=4;aulast=Mortezaeian;type=0 |
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| author | Hojat Mortezaeian Mahmoud Meraji Mohammadreza Naghibi Avisa Tabib Hasan Birjandi Ahmad Vesal Ata Firouzi |
| author_facet | Hojat Mortezaeian Mahmoud Meraji Mohammadreza Naghibi Avisa Tabib Hasan Birjandi Ahmad Vesal Ata Firouzi |
| author_sort | Hojat Mortezaeian |
| collection | DOAJ |
| description | Background: The right ventricular outflow tract (RVOT) palliation has been shown to be a proper interventional procedure for lowering risk of mortality and improving clinical condition in cyanotic congenital heart disease (CHD) patients.
Objectives: The present study aimed to assess the consequences of RVOT palliation in patients with TOF.
Patients and Methods: This prospective case series was performed on 17 children who suffered from cyanotic CHD. The study end- points were assessed by pulse oximetry, echocardiography, and electrocardiography immediately and also 12 months after RVOT palliation procedure.
Results: The mean age of patients was 24.76 (median 10 months). Comparing laboratory and respiratory parameters 12 months after RVOT palliation showed a significant increase in arterial oxygen saturation (from 69.34 ± 13.07 to 86.29 ± 6.64, P= 0.001), RPA index of right pulmonary artery (from 5.49 ± 1.67 mm to 7.59 ± 1.79 mm, P< 0.001), Z score of right pulmonary artery (from-1.56 ± 2.34 to 0.53 ± 2.55, P < 0.001), LPA of left pulmonary artery (from 5.64 ± 1.88 mm to 8.06 ± 2.72 mm, P < 0.001), and also in Z score of left pulmonary artery (from -1.56 ± 2.33 to 0.78 ± 2.15, P = 0.001). Also, a significant decrease in the spell rate (from 88.2% to 17.6%, P < 0.001), and in the rate of tricuspid regurgitation (from 23.5% to 11.8%, P= 0.023) was shown. Cardiac arrhythmia occurred in only one patient that was transient. Stent fracture was found in none of the patients. Stent stenosis was also found in one patient. One-year death occurred only in one child.
Conclusions: The right ventricular outflow tract palliation in children with cyanotic CHD leads to long-term favorable outcome regarding improvement in oxygen saturation, increase in Z score of both left and right pulmonary arteries and also considerable decrease in spell. Also, death and complications are rare following RVOT palliation. |
| first_indexed | 2024-12-11T12:08:43Z |
| format | Article |
| id | doaj.art-2403d161a4ed4b519d82214be2117ad3 |
| institution | Directory Open Access Journal |
| issn | 2251-9572 2251-9580 |
| language | English |
| last_indexed | 2024-12-11T12:08:43Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Research in Cardiovascular Medicine |
| spelling | doaj.art-2403d161a4ed4b519d82214be2117ad32022-12-22T01:07:52ZengWolters Kluwer Medknow PublicationsResearch in Cardiovascular Medicine2251-95722251-95802016-01-01534410.5812/cardiovascmed.31948Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series studyHojat MortezaeianMahmoud MerajiMohammadreza NaghibiAvisa TabibHasan BirjandiAhmad VesalAta FirouziBackground: The right ventricular outflow tract (RVOT) palliation has been shown to be a proper interventional procedure for lowering risk of mortality and improving clinical condition in cyanotic congenital heart disease (CHD) patients. Objectives: The present study aimed to assess the consequences of RVOT palliation in patients with TOF. Patients and Methods: This prospective case series was performed on 17 children who suffered from cyanotic CHD. The study end- points were assessed by pulse oximetry, echocardiography, and electrocardiography immediately and also 12 months after RVOT palliation procedure. Results: The mean age of patients was 24.76 (median 10 months). Comparing laboratory and respiratory parameters 12 months after RVOT palliation showed a significant increase in arterial oxygen saturation (from 69.34 ± 13.07 to 86.29 ± 6.64, P= 0.001), RPA index of right pulmonary artery (from 5.49 ± 1.67 mm to 7.59 ± 1.79 mm, P< 0.001), Z score of right pulmonary artery (from-1.56 ± 2.34 to 0.53 ± 2.55, P < 0.001), LPA of left pulmonary artery (from 5.64 ± 1.88 mm to 8.06 ± 2.72 mm, P < 0.001), and also in Z score of left pulmonary artery (from -1.56 ± 2.33 to 0.78 ± 2.15, P = 0.001). Also, a significant decrease in the spell rate (from 88.2% to 17.6%, P < 0.001), and in the rate of tricuspid regurgitation (from 23.5% to 11.8%, P= 0.023) was shown. Cardiac arrhythmia occurred in only one patient that was transient. Stent fracture was found in none of the patients. Stent stenosis was also found in one patient. One-year death occurred only in one child. Conclusions: The right ventricular outflow tract palliation in children with cyanotic CHD leads to long-term favorable outcome regarding improvement in oxygen saturation, increase in Z score of both left and right pulmonary arteries and also considerable decrease in spell. Also, death and complications are rare following RVOT palliation.http://www.rcvmonline.com/article.asp?issn=2251-9572;year=2016;volume=5;issue=3;spage=4;epage=4;aulast=Mortezaeian;type=0Palliative CareHeart DefectsCongenital |
| spellingShingle | Hojat Mortezaeian Mahmoud Meraji Mohammadreza Naghibi Avisa Tabib Hasan Birjandi Ahmad Vesal Ata Firouzi Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series study Research in Cardiovascular Medicine Palliative Care Heart Defects Congenital |
| title | Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series study |
| title_full | Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series study |
| title_fullStr | Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series study |
| title_full_unstemmed | Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series study |
| title_short | Long-term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease: A case-series study |
| title_sort | long term outcome of the right ventricular outflow tract palliation procedure in children with cyanotic congenital heart disease a case series study |
| topic | Palliative Care Heart Defects Congenital |
| url | http://www.rcvmonline.com/article.asp?issn=2251-9572;year=2016;volume=5;issue=3;spage=4;epage=4;aulast=Mortezaeian;type=0 |
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