In Vivo and In Vitro Characterization of Primary Human Liver Macrophages and Their Inflammatory State

In Vivo and In Vitro Characterization of Primary Human Liver Macrophages and Their Inflammatory State

Liver macrophages (LMs) play a central role in acute and chronic liver pathologies. Investigation of these processes in humans as well as the development of diagnostic tools and new therapeutic strategies require in vitro models that closely resemble the in vivo situation. In our study, we sought to...

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Bibliographic Details
Main Authors: Andrea Zimmermann, René Hänsel, Kilian Gemünden, Victoria Kegel-Hübner, Jonas Babel, Hendrik Bläker, Madlen Matz-Soja, Daniel Seehofer, Georg Damm
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
human liver
liver cell isolation
primary human liver cells
hepatic macrophages
Kupffer cells
monocyte-derived macrophages
Online Access:https://www.mdpi.com/2227-9059/9/4/406

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