Quantum-Dot-Based Iron Oxide Nanoparticles Activate the NLRP3 Inflammasome in Murine Bone Marrow-Derived Dendritic Cells

Quantum-Dot-Based Iron Oxide Nanoparticles Activate the NLRP3 Inflammasome in Murine Bone Marrow-Derived Dendritic Cells

Inflammasomes are cytosolic complexes composed of a Nod-like receptor, NLR, the adaptor protein, ASC, and a proteolytic enzyme, caspase-1. Inflammasome activation leads to caspase-1 activation and promotes functional maturation of IL-1β and IL-18, two prototypical inflammatory cytokines. Besides, in...

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Bibliographic Details
Main Authors: Fernando Menegatti de Melo, Karine Kawasaki, Tarciso Almeida Sellani, Bruno Souza Bonifácio, Renato Arruda Mortara, Henrique Eisi Toma, Filipe Menegatti de Melo, Elaine Guadelupe Rodrigues
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Nanomaterials
Subjects:
quantum-dot
iron oxide nanoparticles
NLRP inflammasome
dendritic cells
Online Access:https://www.mdpi.com/2079-4991/12/18/3145

Internet

https://www.mdpi.com/2079-4991/12/18/3145

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