ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASES

There is no report on the etiology of acute viral hepatitis in Sistan and Baluchestan province, southeast of Iran. We performed this study to compare the clinical, biochemical and demographic properties of acute viral hepatitis (AVH) in this province. Demographic and clinical data were collected fro...

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Main Authors: M Salehi, M Izadi, N Bazzaz, N Jonaidi, R Ranjbar, H Khedmat
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2008-10-01
Series:Acta Medica Iranica
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/3511
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author M Salehi
M Izadi
N Bazzaz
N Jonaidi
R Ranjbar
H Khedmat
author_facet M Salehi
M Izadi
N Bazzaz
N Jonaidi
R Ranjbar
H Khedmat
author_sort M Salehi
collection DOAJ
description There is no report on the etiology of acute viral hepatitis in Sistan and Baluchestan province, southeast of Iran. We performed this study to compare the clinical, biochemical and demographic properties of acute viral hepatitis (AVH) in this province. Demographic and clinical data were collected from 263 patients with AVH. They were tested for HBsAg, IgM anti-HAV, IgM anti-HBc, IgM anti-HDV, or IgM anti-HCV. Numbers of patients with hepatitis A, B, C, D and non A-D were: 188 (75.5%), 47 (17.9%), 6 (2.3%), 5(1.9%) and 17(6.6%), while mean ages were 6.1, 20.6, 20.2, 26.2 and 18.7 years, respectively. Hepatitis A patients presented with lower initial serum levels of bilirubin, ALT and AST, but higher alkaline phosphatase, and they were more likely to have anorexia, vomiting, fever, chills, abdominal pain and prodromal symptoms. Nearly all cases of AVH in children were due to Hepatitis A, whereas hepatitis B, C and D generally occurred in adults. There were some differences in clinical and laboratory findings regarding to the etiology.
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spelling doaj.art-24183b408d3f4fe79fa2582287ebf7242022-12-21T23:27:10ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942008-10-01465ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASESM Salehi0M Izadi1N Bazzaz2N Jonaidi3R Ranjbar4H Khedmat51) Department of Infectious Diseases, School of Medicine, Zahedan University of Medical Sciences and2) Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran2) Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran2) Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran3) Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran 4) Gastrointestinal Research Center, School of Medicine, Baqiyatallah University of Medical SciencesThere is no report on the etiology of acute viral hepatitis in Sistan and Baluchestan province, southeast of Iran. We performed this study to compare the clinical, biochemical and demographic properties of acute viral hepatitis (AVH) in this province. Demographic and clinical data were collected from 263 patients with AVH. They were tested for HBsAg, IgM anti-HAV, IgM anti-HBc, IgM anti-HDV, or IgM anti-HCV. Numbers of patients with hepatitis A, B, C, D and non A-D were: 188 (75.5%), 47 (17.9%), 6 (2.3%), 5(1.9%) and 17(6.6%), while mean ages were 6.1, 20.6, 20.2, 26.2 and 18.7 years, respectively. Hepatitis A patients presented with lower initial serum levels of bilirubin, ALT and AST, but higher alkaline phosphatase, and they were more likely to have anorexia, vomiting, fever, chills, abdominal pain and prodromal symptoms. Nearly all cases of AVH in children were due to Hepatitis A, whereas hepatitis B, C and D generally occurred in adults. There were some differences in clinical and laboratory findings regarding to the etiology.https://acta.tums.ac.ir/index.php/acta/article/view/3511
spellingShingle M Salehi
M Izadi
N Bazzaz
N Jonaidi
R Ranjbar
H Khedmat
ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASES
Acta Medica Iranica
title ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASES
title_full ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASES
title_fullStr ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASES
title_full_unstemmed ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASES
title_short ACUTE VIRAL HEPATITIS IN SOUTH-EAST OF IRAN: A SEROLOGICAL ANALYSIS OF 263 CASES
title_sort acute viral hepatitis in south east of iran a serological analysis of 263 cases
url https://acta.tums.ac.ir/index.php/acta/article/view/3511
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AT nbazzaz acuteviralhepatitisinsoutheastofiranaserologicalanalysisof263cases
AT njonaidi acuteviralhepatitisinsoutheastofiranaserologicalanalysisof263cases
AT rranjbar acuteviralhepatitisinsoutheastofiranaserologicalanalysisof263cases
AT hkhedmat acuteviralhepatitisinsoutheastofiranaserologicalanalysisof263cases