Increased Circulating ADMA in Young Male Rats Caused Cognitive Deficits and Increased Intestinal and Hippocampal NLRP3 Inflammasome Expression and Microbiota Composition Alterations: Effects of Resveratrol

Increased Circulating ADMA in Young Male Rats Caused Cognitive Deficits and Increased Intestinal and Hippocampal NLRP3 Inflammasome Expression and Microbiota Composition Alterations: Effects of Resveratrol

Endothelial dysfunction is characterized by disturbances in nitric oxide (NO) bioavailability and increased circulating asymmetric dimethylarginine (ADMA) due to the enormous release of free radicals. Increased circulating ADMA may cause endothelial dysfunction and a variety of clinical disorders, s...

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Bibliographic Details
Main Authors: Mei-Hsin Hsu, Yi-Chuan Huang, Yu-Chieh Chen, Jiunn-Ming Sheen, Li-Tung Huang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceuticals
Subjects:
asymmetric dimethylarginine
endothelium
NLRP3 inflammasome
microbiota
resveratrol
cognition
Online Access:https://www.mdpi.com/1424-8247/16/6/825

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